The outdoor air pollution and brain health workshop

…, SS Nadadur, B Ritz, EO Semmens, LH Tonelli… - Neurotoxicology, 2012 - Elsevier
Accumulating evidence suggests that outdoor air pollution may have a significant impact on
central nervous system (CNS) health and disease. To address this issue, the National …

Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor

…, J Lovett, EFR Pereira, SM Clark, LH Tonelli… - Nature …, 2022 - nature.com
We show that the sex of human experimenters affects mouse behaviors and responses following
administration of the rapid-acting antidepressant ketamine and its bioactive metabolite (…

Elevated cytokine expression in the orbitofrontal cortex of victims of suicide

LH Tonelli, J Stiller, D Rujescu… - Acta Psychiatrica …, 2008 - Wiley Online Library
Objective: Based on the reported association between cytokines with depression and
suicide, and evidence of increased markers of inflammation in the brain of suicide victims, the …

Toxoplasma gondii antibody titers and history of suicide attempts in patients with recurrent mood disorders

…, JA Cabassa, DA Scrandis, LH Tonelli… - The Journal of …, 2009 - journals.lww.com
Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite infecting one-third
of the world population, residing relatively silently in the brain of the immunocompetent …

[HTML][HTML] Intranasal immune challenge induces sex-dependent depressive-like behavior and cytokine expression in the brain

LH Tonelli, A Holmes, TT Postolache - Neuropsychopharmacology, 2008 - nature.com
The association between activation of the immune system and mood disorders has been
reported by several studies. However, the mechanisms by which the immune system affects …

Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents

LH Tonelli, M Katz, CE Kovacsics, TD Gould… - Brain, behavior, and …, 2009 - Elsevier
Epidemiological and clinical studies report higher incidences of anxiety and increased
emotional reactivity in individuals suffering from respiratory allergies. To evaluate if respiratory …

Seasonal spring peaks of suicide in victims with and without prior history of hospitalization for mood disorders

TT Postolache, PB Mortensen, LH Tonelli, X Jiao… - Journal of affective …, 2010 - Elsevier
BACKGROUND: Seasonal spring peaks of suicide are highly replicated, but their origin is
poorly understood. As the peak of suicide in spring could be a consequence of …

Allergy: a risk factor for suicide?

TT Postolache, H Komarow, LH Tonelli - Current treatment options in …, 2008 - Springer
Opinion statement The rates of depression, anxiety, and sleep disturbance (suicide risk
factors) are greater in patients with allergic rhinitis than in the general population. The rate of …

Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals

…, J Stiller, TT Postolache, R Schwarcz, LH Tonelli - Journal of Psychiatry and …, 2016 - jpn.ca
Background: Neuroinflammatory processes are increasingly believed to participate in the
pathophysiology of a number of major psychiatric diseases, including depression. Immune …

[HTML][HTML] Long-term persistence of infectious Zika virus: inflammation and behavioral sequela in mice

…, IL McWilliams, L Kelley-Baker, LH Tonelli… - Plos …, 2020 - journals.plos.org
The neurodevelopmental defects associated with ZIKV infections early in pregnancy are well
documented, however the potential defects and long-term consequences associated with …