The outdoor air pollution and brain health workshop
…, SS Nadadur, B Ritz, EO Semmens, LH Tonelli… - Neurotoxicology, 2012 - Elsevier
Accumulating evidence suggests that outdoor air pollution may have a significant impact on
central nervous system (CNS) health and disease. To address this issue, the National …
central nervous system (CNS) health and disease. To address this issue, the National …
Experimenters' sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor
…, J Lovett, EFR Pereira, SM Clark, LH Tonelli… - Nature …, 2022 - nature.com
We show that the sex of human experimenters affects mouse behaviors and responses following
administration of the rapid-acting antidepressant ketamine and its bioactive metabolite (…
administration of the rapid-acting antidepressant ketamine and its bioactive metabolite (…
Elevated cytokine expression in the orbitofrontal cortex of victims of suicide
LH Tonelli, J Stiller, D Rujescu… - Acta Psychiatrica …, 2008 - Wiley Online Library
Objective: Based on the reported association between cytokines with depression and
suicide, and evidence of increased markers of inflammation in the brain of suicide victims, the …
suicide, and evidence of increased markers of inflammation in the brain of suicide victims, the …
Toxoplasma gondii antibody titers and history of suicide attempts in patients with recurrent mood disorders
…, JA Cabassa, DA Scrandis, LH Tonelli… - The Journal of …, 2009 - journals.lww.com
Toxoplasma gondii (T. gondii) is an obligate intracellular protozoan parasite infecting one-third
of the world population, residing relatively silently in the brain of the immunocompetent …
of the world population, residing relatively silently in the brain of the immunocompetent …
[HTML][HTML] Intranasal immune challenge induces sex-dependent depressive-like behavior and cytokine expression in the brain
LH Tonelli, A Holmes, TT Postolache - Neuropsychopharmacology, 2008 - nature.com
The association between activation of the immune system and mood disorders has been
reported by several studies. However, the mechanisms by which the immune system affects …
reported by several studies. However, the mechanisms by which the immune system affects …
Allergic rhinitis induces anxiety-like behavior and altered social interaction in rodents
Epidemiological and clinical studies report higher incidences of anxiety and increased
emotional reactivity in individuals suffering from respiratory allergies. To evaluate if respiratory …
emotional reactivity in individuals suffering from respiratory allergies. To evaluate if respiratory …
Seasonal spring peaks of suicide in victims with and without prior history of hospitalization for mood disorders
TT Postolache, PB Mortensen, LH Tonelli, X Jiao… - Journal of affective …, 2010 - Elsevier
BACKGROUND: Seasonal spring peaks of suicide are highly replicated, but their origin is
poorly understood. As the peak of suicide in spring could be a consequence of …
poorly understood. As the peak of suicide in spring could be a consequence of …
Allergy: a risk factor for suicide?
TT Postolache, H Komarow, LH Tonelli - Current treatment options in …, 2008 - Springer
Opinion statement The rates of depression, anxiety, and sleep disturbance (suicide risk
factors) are greater in patients with allergic rhinitis than in the general population. The rate of …
factors) are greater in patients with allergic rhinitis than in the general population. The rate of …
Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals
…, J Stiller, TT Postolache, R Schwarcz, LH Tonelli - Journal of Psychiatry and …, 2016 - jpn.ca
Background: Neuroinflammatory processes are increasingly believed to participate in the
pathophysiology of a number of major psychiatric diseases, including depression. Immune …
pathophysiology of a number of major psychiatric diseases, including depression. Immune …
[HTML][HTML] Long-term persistence of infectious Zika virus: inflammation and behavioral sequela in mice
…, IL McWilliams, L Kelley-Baker, LH Tonelli… - Plos …, 2020 - journals.plos.org
The neurodevelopmental defects associated with ZIKV infections early in pregnancy are well
documented, however the potential defects and long-term consequences associated with …
documented, however the potential defects and long-term consequences associated with …