OBJECTIVE: Because of the irreversibility of lesioning procedures and their possible side
effects, we studied the efficacy of replacing bilateral anterior capsulotomy with chronic …

Objective: Investigation of deep brain stimulation (DBS) as a last‐resort treatment alternative
to capsulotomy in treatment‐refractory obsessive‐compulsive disorder (OCD). Method: …

… Loes Gabriëls is holder of the Chair for neurosurgery in psychiatric disorders at the KU
Leuven, funded by Medtronic. Damiaan Denys and Rick Schuurman received unrestricted grants …

In 1998, we proposed deep brain stimulation as a last-resort treatment option for patients
suffering from severe, treatment-resistant obsessive-compulsive disorder (OCD). Here, 24 OCD …

Background For patients with psychiatric illnesses remaining refractory to ‘standard’ therapies,
neurosurgical procedures may be considered. Guidelines for safe and ethical conduct of …

Context A 2-day consensus conference was held to examine scientific and ethical issues in
the application of deep brain stimulation for treating mood and behavioral disorders, such as …

Objective Anorexia nervosa (AN) is a complex and severe, sometimes life-threatening,
psychiatric disorder with high relapse rates under standard treatment. After decades of brain-…

Functional neuroimaging is widely used to unravel changes in brain functioning in
psychiatric disorders. In the current study, we review single-photon emission tomography (SPECT), …

A consensus has yet to emerge whether deep brain stimulation (DBS) for treatment-refractory
obsessive-compulsive disorder (OCD) can be considered an established therapy. In 2014, …

Background: In patients seeking aesthetic rhinoplasty, a high prevalence of body dysmorphic
disorder symptoms has recently been reported. However, the impact of these symptoms on …