Significance: Severe life stress (SLS), as opposed to trivial everyday stress, is defined as a
serious psychosocial event with the potential of causing an impacting psychological …

Extracellular ATP is a mediator of intercellular communication and a danger signal. Release
of this and other nucleotides modulates microglia responses via P2Y and P2X receptors, …

BACKGROUND: Social stress leads to oxidative stress in the central nervous system,
contributing to the development of mental disorders. Loss of parvalbumin in interneurons is an …

Rationale It has been suggested that endocannabinoid mechanisms are involved in the
control of ethanol consumption. Objectives The aims of the present study were (1) to evaluate …

In the last several years a large number of studies have demonstrated the neurobiological
and clinical continuum between depression and Alzheimer’s disease (AD). Depression is a …

Background: Amyloid-β oligomers (AβO) are species mainly involved in the synaptic and
cognitive dysfunction in Alzheimer’s disease. Although their action has been described mainly …

Previous studies have provided extensive evidence that administration of cannabinoid
drugs after training modulates the consolidation of memory for an aversive experience. The …

Oregano and thyme essential oils are used for therapeutic, aromatic and gastronomic purposes
due to their richness in active substances, like carvacrol; however, the effects of the latter …

The aim of this study was to investigate whether prenatal exposure to the cannabinoid CB1
receptor agonist WIN 55,212-2 (WIN) at a daily dose devoid of overt signs of toxicity and/or …

Importance Convalescent plasma (CP) has been generally unsuccessful in preventing
worsening of respiratory failure or death in hospitalized patients with COVID-19 pneumonia. …