Several species of Passiflora have been employed widely as a folk medicine because of
sedative and tranquillizer activities. In this study, we evaluate the effects on anxiety and memory …

Objective: Previous studies have suggested that oxidative stress may play a role in the
pathophysiology of bipolar disorder (BD). Moreover, recent studies indicate that lithium and …

Vários estudos em humanos e animais têm demonstrado que a formação da memória é
facilitada por um sistema modulatório endógeno, mediado pela liberação de hormônios de …

There is an emerging body of data suggesting that mood disorders are associated with
decreased brain-derived neurotrophic factor (BDNF). The present study aims to investigate the …

Objective: Critical illness survivors present long-term cognitive impairment, including problems
with memory and learning. We evaluated cognitive performance in rats that survived from …

Methylphenidate (MPH) is frequently prescribed for the treatment of attention deficit/hyperactivity
disorder. Psychostimulants can cause long-lasting neurochemical and behavioral …

Typical and atypical antipsychotic drugs have been shown to have different clinical and
behavioral profiles. Haloperidol (HAL) is a typical neuroleptic that acts primarily as a D 2 …

Studies have demonstrated that oxidative stress is associated with amphetamine-induced
neurotoxicity, but little is known about the adaptations of antioxidant enzymes in the brain after …

Previous studies have suggested that reactive oxygen species (ROS) production may play a
role in the pathophysiology of many neuropsychiatric disorders, such as bipolar disorder (…

… This work was supported by CAPES–EMBRAPA agreement (post-doctoral scholarship to
Márcio R. Martins) and with the research grants “Cientista do Nosso Estado” from FAPERJ …