Increasing evidence indicates that ovarian hormones affect brain structure, chemistry and
function of women in their reproductive age, potentially shaping their behavior and mental …

Ovarian hormones fluctuations across the menstrual cycle are experienced by about 58% of
women in their fertile age. Maladaptive brain sensitivity to these changes likely leads to the …

Endocrine organizational and activational influences on cognitive and affective circuits are
likely critical to the development of premenstrual dysphoric disorder (PMDD), a sex-specific …

Premenstrual dysphoric disorder (PMDD) is a psychiatric condition characterized by late
luteal phase affective, cognitive, and physical impairment. The disorder causes significant …

Premenstrual dysphoric disorder (PMDD) is a female-specific condition classified in the
Diagnostic and Statical Manual—5th edition under depressive disorders. Alterations in grey …

Dopamine function and reward processing are highly interrelated and involve common
brain regions afferent to the nucleus accumbens, within the mesolimbic pathway. Although …

Background: Premenstrual dysphoric disorder (PMDD) is a mood disorder characterized by
psychological and physical symptoms. Differences in white matter have been associated …

Neuroimaging studies investigating dopamine (DA) function widely support the hypothesis
of presynaptic striatal DA hyperactivity in schizophrenia. However, published data on the …

Premenstrual dysphoric disorder (PMDD) is characterized by severe cyclic mood symptoms
emerging in the luteal phase of the menstrual cycle. The variation in progesterone levels …

Background A reduced presynaptic dopamine neurotransmission has long been implicated
in major depressive disorder (MDD). However, molecular imaging studies that assessed the …