SPECT of serotonin transporters using 123I-ADAM: optimal imaging time after bolus injection and long-term test–retest in healthy volunteers

…, MM Penengo, S Bullich, M Danús… - Journal of Nuclear …, 2005 - Soc Nuclear Med
123 I-ADAM (2-([2-([dimethylamino]methyl)phenyl]thio)-5- 123 I-iodophenylamine) has been
recently proposed as a new serotonin transporter (SERT) ligand for SPECT. The objective …

Serotonin transporter occupancy induced by paroxetine in patients with major depression disorder: a 123I-ADAM SPECT study

…, JC Pascual, S Bullich, M Suarez, MM Penengo… - …, 2006 - Springer
Rationale To assess the paroxetine-induced serotonin transporter (SERT) occupancy (SERTocc)
using in vivo 123 I-ADAM SPECT. Objectives 123 I-ADAM SPECT was used to …

Pharmacokinetics and time-course of D2 receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients

AM Catafau, MM Penengo, G Nucci… - Journal of …, 2008 - journals.sagepub.com
The 123 I-IBZM SPECT measured D 2 receptor occupancy (D 2 RO) in chronically dosed,
stabilized schizophrenic patients and its relationship with antipsychotic (AP) pharmacokinetics (…

Test–retest variability and reliability of 123I‐IBZM SPECT measurement of striatal dopamine D2 receptor availability in healthy volunteers and influence of iterative …

AM Catafau, S Bullich, M Danús, MM Penengo… - Synapse, 2008 - Wiley Online Library
Objective: 123 I‐IBZM single photon emission computed tomography (SPECT) is a widely
used method to measure D 2 receptor availability. However, test–retest variability and …

Characterization of the SPECT 5-HT2A receptor ligand 123I-R91150 in healthy volunteers: part 1—pseudoequilibrium interval and quantification methods

…, VJ Cunningham, P Plaza, MM Penengo… - Journal of Nuclear …, 2006 - Soc Nuclear Med
With the aim of characterizing radioiodinated 4-amino-N-1-[3-(4-fluorophenoxy)propyl]-4-methyl-4-piperidinyl]5-iodo-2-methoxybenzamide
( 123 I-R91150) as a SPECT ligand for …

… & PKPD approach to estimate the time course of antipsychotic-induced D2 occupancy Gianluca Nucci (1), Ana M. Catafau (2), María M. Penengo (3), Santiago Bullich …

G Nucci - page-meeting.org
Background: Blockade of dopamine D2 receptors (D2RO) is a common feature of all
antipsychotics (AP) and is a predictor of clinical response and of side effects of AP [1-3]. However, …

[PDF][PDF] Psicodélicos:¿ retorno de lo reprimido?

M Toledo, M Penengo, J Pablo - Rev Psiquiatr Urug, 2022 - spu.org.uy
¿ Es posible desarrollar investigaciones clínicas utilizando sustancias psicodélicas en
Uruguay? Pasado y presente de las investigaciones sobre el potencial medicinal de los …

[PDF][PDF] Psiquiatría y evidencia: lecciones de la pandemia

M Toledo, M Penengo, JP García - Rev Psiquiatr Urug, 2020 - spu.org.uy
Correspondencia: mauricio. toledo1@ gmail. com permitiendo tomar decisiones en la clínica.
Uno es el estudio Recovery1 y el otro es el estudio Solidarity. 2 Lo destacamos porque a …

[PDF][PDF] Depresión: más allá del mito de la serotonina

M Toledo, F Lozano, M Penengo, I Olmos… - Rev. psiquiatr …, 2022 - researchgate.net
Antonio Machado, Proverbios y cantares and antidepressant benefits: a meta-analysis of
data submitted to the Food and Drug Administration” 4 y el libro “The emperor’s new drugs: …

[PDF][PDF] Psicodélicos:¿ disputan el campo terapéutico?

M Toledo, M Penengo, F Lozano, I Carrera, I Apud… - scholar.archive.org
aclarar que los psicodélicos no tienen aprobación formal por parte de las agencias reguladoras
para su uso en la práctica clínica diaria. Desde una mirada categorial, la clasificación …