User profiles for Marek Schwendt
 | Marek SchwendtAssociate Professor of Psychology and Neuroscience, University of Florida Verified email at ufl.edu Cited by 1880 |
Contrasting the role of xCT and GLT-1 upregulation in the ability of ceftriaxone to attenuate the cue-induced reinstatement of cocaine seeking and normalize AMPA …
…, KJ Reissner, M Schwendt… - Journal of …, 2017 - Soc Neuroscience
Long-term treatment with ceftriaxone attenuates the reinstatement of cocaine seeking while
increasing the function of the glutamate transporter 1 (GLT-1) and system xC- (Sxc) in the …
increasing the function of the glutamate transporter 1 (GLT-1) and system xC- (Sxc) in the …
[HTML][HTML] Extinction-dependent alterations in corticostriatal mGluR2/3 and mGluR7 receptors following chronic methamphetamine self-administration in rats
Methamphetamine (meth) is a highly addictive and widely abused psychostimulant. Repeated
use of meth can quickly lead to dependence, and may be accompanied by a variety of …
use of meth can quickly lead to dependence, and may be accompanied by a variety of …
Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking
Learning to inhibit drug seeking can be an important strategy for inhibiting relapse, and this
can be modeled by extinguishing drug seeking in response to a drug-paired context. Rats …
can be modeled by extinguishing drug seeking in response to a drug-paired context. Rats …
[HTML][HTML] A novel rat model of comorbid PTSD and addiction reveals intersections between stress susceptibility and enhanced cocaine seeking with a role for mGlu5 …
M Schwendt, J Shallcross, NA Hadad… - Translational …, 2018 - nature.com
PTSD is highly comorbid with cocaine use disorder (CUD), and cocaine users with PTSD +
CUD are more resistant to treatment. Here we sought to develop a rat model of PTSD + CUD …
CUD are more resistant to treatment. Here we sought to develop a rat model of PTSD + CUD …
[HTML][HTML] Loss of object recognition memory produced by extended access to methamphetamine self-administration is reversed by positive allosteric modulation of …
Chronic methamphetamine (meth) abuse can lead to persisting cognitive deficits. Here, we
utilized a long-access meth self-administration (SA) protocol to assess recognition memory …
utilized a long-access meth self-administration (SA) protocol to assess recognition memory …
[HTML][HTML] The divergent effects of CDPPB and cannabidiol on fear extinction and anxiety in a predator scent stress model of PTSD in rats
…, M Romano, L Knackstedt, M Schwendt - Frontiers in behavioral …, 2019 - frontiersin.org
Post-traumatic stress disorder (PTSD) currently has no FDA-approved treatments that reduce
symptoms in the majority of patients. The ability to extinguish fear memory associations is …
symptoms in the majority of patients. The ability to extinguish fear memory associations is …
The effects of ceftriaxone on cue-primed reinstatement of cocaine-seeking in male and female rats: estrous cycle effects on behavior and protein expression in the …
AR Bechard, PU Hamor, M Schwendt… - …, 2018 - Springer
Rationale Effective pharmacological treatments to prevent cocaine relapse remain elusive.
In male rats, ceftriaxone attenuates the reinstatement of cocaine-seeking while increasing …
In male rats, ceftriaxone attenuates the reinstatement of cocaine-seeking while increasing …
Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not …
Chronic abuse of methamphetamine leads to cognitive dysfunction and high rates of relapse,
paralleled by significant changes of brain dopamine and serotonin neurotransmission. …
paralleled by significant changes of brain dopamine and serotonin neurotransmission. …
Methamphetamine-induced changes in the object recognition memory circuit
Chronic methamphetamine (meth) can lead to persisting cognitive deficits in human addicts
and animal models of meth addiction. Here, we examined the impact of either contingent or …
and animal models of meth addiction. Here, we examined the impact of either contingent or …
The role of ventral and dorsal striatum mGluR5 in relapse to cocaine‐seeking and extinction learning
…, HL Trantham‐Davidson, M Schwendt - Addiction …, 2014 - Wiley Online Library
Cocaine addiction is a chronic, relapsing disease characterized by an inability to regulate
drug‐seeking behavior. Here we investigated the role of mGluR5 in the ventral and dorsal …
drug‐seeking behavior. Here we investigated the role of mGluR5 in the ventral and dorsal …