User profiles for Maria Ironside
 | Maria IronsideLaureate Institute for Brain Research Verified email at laureateinstitute.org Cited by 689 |
Effect of prefrontal cortex stimulation on regulation of amygdala response to threat in individuals with trait anxiety: a randomized clinical trial
Importance Transcranial direct current stimulation (tDCS) of the dorsolateral prefrontal
cortex (DLPFC) is under clinical investigation as a treatment for major depressive disorder. …
cortex (DLPFC) is under clinical investigation as a treatment for major depressive disorder. …
Frontal cortex stimulation reduces vigilance to threat: implications for the treatment of depression and anxiety
Background The difficulty in treating mood disorders has brought about clinical interest in
alternative treatments, such as transcranial direct current stimulation (tDCS) of the dorsolateral …
alternative treatments, such as transcranial direct current stimulation (tDCS) of the dorsolateral …
Brain mechanisms mediating effects of stress on reward sensitivity
Highlights • Stress preferentially perturbates reward anticipation (rather than consumption).
• Cortico–striatal–limbic network dysregulation subserves stress effects on reward. • Probing …
• Cortico–striatal–limbic network dysregulation subserves stress effects on reward. • Probing …
The unique face of anxious depression: Exaggerated threat but preserved valence sensitivity
M Ironside, R Kuplicki, E Walker, C Ramsey… - medRxiv, 2022 - medrxiv.org
Background Despite being the most common psychiatric comorbidity, underlying brain and
behavioral processes characterizing anxious depression are not well understood. Affective …
behavioral processes characterizing anxious depression are not well understood. Affective …
Methodology for tDCS integration with fMRI
Understanding and reducing variability of response to transcranial direct current stimulation
(tDCS) requires measuring what factors predetermine sensitivity to tDCS and tracking …
(tDCS) requires measuring what factors predetermine sensitivity to tDCS and tracking …
[HTML][HTML] The unique face of comorbid anxiety and depression: increased interoceptive fearfulness and reactivity
Anxiety and depression commonly co-occur, yet the underlying brain and behavioral processes
are poorly understood. Here we examined the hypothesis that individuals with comorbid …
are poorly understood. Here we examined the hypothesis that individuals with comorbid …
Elevated decision uncertainty and reduced avoidance drives in depression, anxiety and substance use disorders during approach–avoidance conflict: a replication …
Background: Decision-making under approach–avoidance conflict (AAC; eg, sacrificing
quality of life to avoid feared outcomes) may be affected in multiple psychiatric disorders. …
quality of life to avoid feared outcomes) may be affected in multiple psychiatric disorders. …
The role of the dorsal–lateral prefrontal cortex in reward sensitivity during approach–avoidance conflict
…, N Johnson, K Amemori, M Ironside… - Cerebral …, 2022 - academic.oup.com
Abstract Approach–Avoidance conflict (AAC) arises from decisions with embedded positive
and negative outcomes, such that approaching leads to reward and punishment and …
and negative outcomes, such that approaching leads to reward and punishment and …
Neural response to stress differs by sex in young adulthood
Increase in stress-related disorders in women begins post-puberty and persists throughout
the lifespan. To characterize sex differences in stress response in early adulthood, we used …
the lifespan. To characterize sex differences in stress response in early adulthood, we used …
Approach-avoidance conflict in major depressive disorder: congruent neural findings in humans and nonhuman primates
Background Maladaptive approach-avoidance behavior has been implicated in the
pathophysiology of major depressive disorder (MDD), but the neural basis of these abnormalities in …
pathophysiology of major depressive disorder (MDD), but the neural basis of these abnormalities in …
