MicroRNAs (miRs) are evolutionarily conserved, noncoding RNA molecules of ∼21 nt that
regulate the expression of genes that are involved in various biological processes, such as …

(1) Axons contain numerous mRNAs and a local protein synthetic system that can be regulated
independently of the cell body. (2) In this study, cultured primary sympathetic neurons …

OBJECTIVE—Suppressors of cytokine signaling (SOCS) are implicated in the etiology of
diabetes, obesity, and metabolic syndrome. Here, we show that some SOCS members are …

Obscurins (∼ 70–-870 kDa), encoded by the single OBSCN gene, are cytoskeletal proteins
originally identified in striated muscles with structural and regulatory roles. Recently, …

The postsynaptic density is the ultrastructural entity containing the neurotransmitter reception
apparatus of excitatory synapses in the brain. A recently identified family of multidomain …

Shank/ProSAP proteins are major scaffold proteins of the postsynaptic density; mutations in
the human SHANK3 gene are associated with intellectual disability or autism spectrum …

Previously, pA134 was identified as one of the mRNAs present in the squid giant axon.
Comparative sequence analyses revealed that the pA134 gene product manifested significant …

The molecular cloning of somatostatin (SST) receptors in the early 1990s brought about an
unexpected multiplicity of receptor subtypes (1, 2); whereas only two different types of ligand …

X-linked retinoschisis (RS) is an inherited recessive macular degeneration that affects between
1 in 5000 and 1 in 25,000 males early in life (George et al., 1995; Sieving, 1998; Tantri et …

… The monomeric Gactin undergoes constant turnover between adenosine diphosphate (ADP)-
and ATPbound states. ATP-bound G-actin can form more stable oligomers via non-…