Activation of microglia by amyloid β requires P2X7 receptor expression

JM Sanz, P Chiozzi, D Ferrari, M Colaianna… - The Journal of …, 2009 - journals.aai.org
Extracellular ATP is a mediator of intercellular communication and a danger signal. Release
of this and other nucleotides modulates microglia responses via P2Y and P2X receptors, …

Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats

…, S Sorce, M Dubois-Dauphin, V Jaquet, M Colaianna… - Biological …, 2009 - Elsevier
BACKGROUND: Social stress leads to oxidative stress in the central nervous system,
contributing to the development of mental disorders. Loss of parvalbumin in interneurons is an …

[HTML][HTML] Carvacrol: from ancient flavoring to neuromodulatory agent

M Zotti, M Colaianna, MG Morgese, P Tucci… - Molecules, 2013 - mdpi.com
Oregano and thyme essential oils are used for therapeutic, aromatic and gastronomic purposes
due to their richness in active substances, like carvacrol; however, the effects of the latter …

Impact of early life stress on the pathogenesis of mental disorders: relation to brain oxidative stress

S Schiavone, M Colaianna… - Current pharmaceutical …, 2015 - ingentaconnect.com
Stress is an inevitable part of human life and it is experienced even before birth. Stress to
some extent could be considered normal and even necessary for the survival and the regular …

Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress

M Colaianna, S Schiavone, M Zotti, P Tucci… - Antioxidants & redox …, 2013 - liebertpub.com
Aims: Psychosocial stress alters the hypothalamic-pituitary-adrenal axis (HPA-axis). Increasing
evidence shows a link between these alterations and oxidant elevation. Oxidative stress …

The NADPH oxidase NOX2 controls glutamate release: a novel mechanism involved in psychosis-like ketamine responses

…, S Schiavone, P Tucci, M Colaianna… - Journal of …, 2010 - Soc Neuroscience
Subanesthetic doses of NMDA receptor antagonist ketamine induce schizophrenia-like
symptoms in humans and behavioral changes in rodents. Subchronic administration of ketamine …

Nimodipine inhibits IL‐1β release stimulated by amyloid β from microglia

JM Sanz, P Chiozzi, M Colaianna… - British journal of …, 2012 - Wiley Online Library
BACKGROUND AND PURPOSE There is growing evidence that inflammation plays a major
role in the pathogenesis of neural damage caused by deposition of amyloid β (Aβ) in the …

Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes

P Tucci, MG Morgese, M Colaianna, M Zotti… - Steroids, 2012 - Elsevier
An extensive literature has documented adverse effects on mental health in anabolic androgenic
steroids (AAS) abusers. Depression seems a common adverse reaction in AAS abusers…

[HTML][HTML] Memantine prevents memory consolidation failure induced by soluble beta amyloid in rats

…, E Mhillaj, MG Morgese, M Colaianna… - Frontiers in behavioral …, 2014 - frontiersin.org
It has been well documented that β-amyloid (Aβ) peptide accumulation and aggregation in
the brain plays a crucial role in the pathophysiology of Alzheimer’s disease (AD). However, a …

Chronic nandrolone administration induces dysfunction of the reward pathway in rats

M Zotti, P Tucci, M Colaianna, MG Morgese, E Mhillaj… - Steroids, 2014 - Elsevier
Data in animal models and surveys in humans have revealed psychiatric complications of
long-term anabolic androgenic steroid abuse. However, the neurobiochemical mechanisms …