BackgroundLittle is known about the impact of insulin resistance on bipolar disorder.AimsTo
examine the relationships between insulin resistance, type 2 diabetes and clinical course …

Objective: Several papers have reported higher prevalence of diabetes mellitus (DM) type 2
in patients suffering from bipolar disorder (BD). The possible links between these 2 …

Objective: Therapeutic options are limited for treatment-resistant bipolar depression (TRBD).
Insulin resistance (IR) confers increased risk for TRBD. We investigated metformin, an …

Objective: Several studies have reported higher prevalence of obesity in patients suffering
from bipolar disorder (BD). To study the relation of elevated body mass index (BMI) in patients …

The interaction between polarity at onset (PAO) and age at onset (AAO) appears to be
important for interpreting results of previous analyses of AAO in bipolar disorder (BD). Using an …

Objectives: In this study we examined general assessment of functioning (GAF), and its relation
to clinical and demographic factors in bipolar patients. A number of studies, mostly from …

Objectives Suicide is a significant cause of mortality in patients with major affective
disorders ( MAD ), and suicidal behavior and MAD co‐aggregate in families. However, the …

Objective This study aimed to examine differences in the clinical presentation of very‐early‐onset
( VEO ) and early‐onset ( EO ) bipolar disorder ( BD ) not fully explored previously. …

Cross-sectional studies indicate that comorbid insulin resistance (IR) and type 2 diabetes
are associated with a more severe course of bipolar disorder (BD); however, this relationship …

Objective: Rapid cycling (RC) affects 13–30% of bipolar patients. Most of the data regarding
RC have been obtained in tertiary care research centers. Generalizability of these findings …