A link between serotonin-related gene polymorphisms, amygdala activity, and placebo-induced relief from social anxiety
Placebo may yield beneficial effects that are indistinguishable from those of active medication,
but the factors underlying proneness to respond to placebo are widely unknown. Here, we …
but the factors underlying proneness to respond to placebo are widely unknown. Here, we …
Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo
…, M Grohp, M Bergström, EM Pich, LG Nilsson, M Bani… - Biological …, 2005 - Elsevier
BACKGROUND: Evidence is accumulating that pharmacological blockade of the substance
P preferring neurokinin-1 (NK1) receptor reduces anxiety. This study compared the effects of …
P preferring neurokinin-1 (NK1) receptor reduces anxiety. This study compared the effects of …
Imaging dopamine D3 receptors in the human brain with positron emission tomography,[11C] PHNO, and a selective D3 receptor antagonist
BACKGROUND: Dopamine D 3 receptors are involved in the pathophysiology of several
neuropsychiatric conditions. [ 11 C]-(+)-PHNO is a radiolabeled D 2 and D 3 agonist, suitable …
neuropsychiatric conditions. [ 11 C]-(+)-PHNO is a radiolabeled D 2 and D 3 agonist, suitable …
[HTML][HTML] Does the MDS-UPDRS provide the precision to assess progression in early Parkinson's disease? Learnings from the Parkinson's progression marker initiative …
A Regnault, B Boroojerdi, J Meunier, M Bani… - Journal of …, 2019 - Springer
Objectives Developing disease modifying therapies for Parkinson’s disease (PD) calls for
outcome measurement strategies focused on characterizing early stage disease progression. …
outcome measurement strategies focused on characterizing early stage disease progression. …
[HTML][HTML] Occupancy of brain dopamine D3 receptors and drug craving: a translational approach
…, A Andorn, E Merlo Pich, M Bani - …, 2013 - nature.com
Selective dopamine D 3 receptor (D 3 R) antagonists prevent reinstatement of drug-seeking
behavior and decrease the rewarding effects of contextual cues associated with drug intake …
behavior and decrease the rewarding effects of contextual cues associated with drug intake …
[HTML][HTML] In vivo effects of the alpha-synuclein misfolding inhibitor minzasolmin supports clinical development in Parkinson's disease
…, R Angers, A Cardenas, MK Prato, M Bani… - npj Parkinson's …, 2023 - nature.com
Direct targeting of alpha-synuclein (ASYN) has emerged as a disease-modifying strategy for
Parkinson’s disease and other synucleinopathies which is being approached using both …
Parkinson’s disease and other synucleinopathies which is being approached using both …
Phase 1/1b Studies of UCB0599, an Oral Inhibitor of α‐Synuclein Misfolding, Including a Randomized Study in Parkinson's Disease
…, M Germani, C Domange, AL Biere, M Bani… - Movement …, 2022 - Wiley Online Library
Background Parkinson's disease (PD) and its progression are thought to be caused and
driven by misfolding of α‐synuclein (ASYN). UCB0599 is an oral, small‐molecule inhibitor of …
driven by misfolding of α‐synuclein (ASYN). UCB0599 is an oral, small‐molecule inhibitor of …
[HTML][HTML] Amygdala subregions tied to SSRI and placebo response in patients with social anxiety disorder
The amygdala is a key structure in the pathophysiology of anxiety disorders, and a putative
target for anxiolytic treatments. Selective serotonin reuptake inhibitors (SSRIs) and placebo …
target for anxiolytic treatments. Selective serotonin reuptake inhibitors (SSRIs) and placebo …
The effects of the dopamine D3 receptor antagonist GSK598809 on attentional bias to palatable food cues in overweight and obese subjects
The mesolimbic dopamine system plays a critical role in the reinforcing effects of rewards.
Evidence from pre-clinical studies suggests that D 3 receptor antagonists may attenuate the …
Evidence from pre-clinical studies suggests that D 3 receptor antagonists may attenuate the …
[HTML][HTML] In vivo imaging of cerebral dopamine D3 receptors in alcoholism
Animal studies support the role of the dopamine D3 receptor (DRD3) in alcohol reinforcement
or liking. Sustained voluntary alcohol drinking in rats has been associated with an …
or liking. Sustained voluntary alcohol drinking in rats has been associated with an …
