User profiles for Michael J. Meaney
Michael J MeaneySingapore Institute for Clinical Sciences (A*STAR) Verified email at mcgill.ca Cited by 118789 |
Epigenetic programming by maternal behavior
Here we report that increased pup licking and grooming (LG) and arched-back nursing (ABN)
by rat mothers altered the offspring epigenome at a glucocorticoid receptor (GR) gene …
by rat mothers altered the offspring epigenome at a glucocorticoid receptor (GR) gene …
Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress
…, S Sharma, D Pearson, PM Plotsky, MJ Meaney - Science, 1997 - science.org
Variations in maternal care affect the development of individual differences in neuroendocrine
responses to stress in rats. As adults, the offspring of mothers that exhibited more licking …
responses to stress in rats. As adults, the offspring of mothers that exhibited more licking …
Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
MJ Meaney - Annual review of neuroscience, 2001 - annualreviews.org
▪ Abstract Naturally occurring variations in maternal care alter the expression of genes that
regulate behavioral and endocrine responses to stress, as well as hippocampal synaptic …
regulate behavioral and endocrine responses to stress, as well as hippocampal synaptic …
Socioeconomic status and the brain: mechanistic insights from human and animal research
Human brain development occurs within a socioeconomic context and childhood socioeconomic
status (SES) influences neural development — particularly of the systems that subserve …
status (SES) influences neural development — particularly of the systems that subserve …
Epigenetics and the biological definition of gene× environment interactions
MJ Meaney - Child development, 2010 - Wiley Online Library
Variations in phenotype reflect the influence of environmental conditions during development
on cellular functions, including that of the genome. The recent integration of epigenetics …
on cellular functions, including that of the genome. The recent integration of epigenetics …
Variations in maternal care in the rat as a mediating influence for the effects of environment on development
Variations in maternal care have been widely considered as a critical influence in development.
In the rat, variations in maternal behavior, particularly in licking/grooming, regulate the …
In the rat, variations in maternal behavior, particularly in licking/grooming, regulate the …
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life
…, S Dymov, S Sharma, MJ Meaney… - Journal of …, 2005 - Soc Neuroscience
Stress responses in the adult rat are programmed early in life by maternal care and
associated with epigenomic marking of the hippocampal exon 1 7 glucocorticoid receptor (GR) …
associated with epigenomic marking of the hippocampal exon 1 7 glucocorticoid receptor (GR) …
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
Maternal care influences hypothalamic-pituitary-adrenal (HPA) function in the rat through
epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse …
epigenetic programming of glucocorticoid receptor expression. In humans, childhood abuse …
Nongenomic transmission across generations of maternal behavior and stress responses in the rat
In the rat, variations in maternal care appear to influence the development of behavioral and
endocrine responses to stress in the offspring. The results of cross-fostering studies …
endocrine responses to stress in the offspring. The results of cross-fostering studies …
Cortisol levels during human aging predict hippocampal atrophy and memory deficits
…, M Thakur, BS McEwen, RL Hauger, MJ Meaney - Nature …, 1998 - nature.com
Elevated glucocorticoid levels produce hippocampal dysfunction and correlate with individual
deficits in spatial learning in aged rats. Previously we related persistent cortisol increases …
deficits in spatial learning in aged rats. Previously we related persistent cortisol increases …