Serotonin (5‐HT) is a neurotransmitter which exerts both central and peripheral control on
numerous physiological functions such as sleep/wake cycle, thermoregulation, food intake, …

In mammals, the hormone melatonin is mainly produced by the pineal gland with nocturnal
peak levels. Its peripheral and central actions rely either on its intrinsic antioxidant properties …

Endoplasmic reticulum (ER) release and cell-surface export of many G protein-coupled
receptors (GPCRs) are tightly regulated. For gamma-aminobutyric acid (GABA) B receptors of …

The 5-HT 1A receptor (5-HT 1A R) is the most extensively characterized serotonin (5-HT)
receptor mainly because of its involvement in the mode of action of antidepressants. The 5-HT …

Selective serotonin reuptake inhibitors are among the most prescribed antidepressants.
Fluoxetine is the lead molecule which exerts its therapeutic effects, at least in part, by promoting …

Serotonin receptors (5-HTRs) mediate both central and peripheral control on numerous
physiological functions such as sleep/wake cycle, thermoregulation, food intake, nociception, …

Human post-natal neurodevelopmental delay is often associated with cerebral alterations
that can lead, by themselves or associated with peripheral deficits, to premature death. Here, …

Although essential for their neuronal function, the molecular mechanisms underlying the
dendritic targeting of serotonin G-protein-coupled receptors are poorly understood. Here, we …

Selective serotonin reuptake inhibitors (SSRI) are aimed at increasing brain 5-HT tone;
however, this expected effect has a slow onset after starting SSRI treatment because of initial …

The 5-HT 3 receptors are serotonin-gated ion channels that physically couple with purinergic
P2X2 receptors to trigger a functional cross-inhibition leading to reciprocal channel …