Ozone air pollution is associated with acute myocardial infarction

JB Ruidavets, M Cournot, S Cassadou, M Giroux… - Circulation, 2005 - Am Heart Assoc
Background— Despite the diversity of the studied health outcomes, types and levels of
pollution, and various environmental settings, there is substantial evidence for a positive link …

A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy

…, G Luna, JN Rauch, SA Reis, M Giroux… - Science translational …, 2019 - science.org
Tau inclusions are a shared feature of many neurodegenerative diseases, among them
frontotemporal dementia caused by tau mutations. Treatment approaches for these conditions …

[HTML][HTML] Amphetamine disrupts dopamine axon growth in adolescence by a sex-specific mechanism in mice

…, J Zhao, JM Restrepo-Lozano, M Giroux… - Nature …, 2023 - nature.com
Initiating drug use during adolescence increases the risk of developing addiction or other
psychopathologies later in life, with long-term outcomes varying according to sex and exact …

miR-218 in adolescence predicts and mediates vulnerability to stress

A Torres-Berrío, A Morgunova, M Giroux, S Cuesta… - Biological …, 2021 - Elsevier
Background Adolescence is a period of increased vulnerability to psychiatric disorders,
including depression. Discovering novel biomarkers to identify individuals who are at high risk is …

Unique effects of social defeat stress in adolescent male mice on the Netrin-1/DCC pathway, prefrontal cortex dopamine and cognition

P Vassilev, AH Pantoja-Urban, M Giroux, D Nouel… - Eneuro, 2021 - eneuro.org
For some individuals, social stress is a risk factor for psychiatric disorders characterized by
adolescent onset, prefrontal cortex (PFC) dysfunction and cognitive impairments. Social …

[PDF][PDF] Enhanced neuronal regeneration in the CAST/Ei mouse strain is linked to expression of differentiation markers after injury

V Lisi, B Singh, M Giroux, E Guzman, MW Painter… - Cell reports, 2017 - cell.com
Peripheral nerve regeneration after injury requires a broad program of transcriptional changes.
We investigated the basis for the enhanced nerve regenerative capacity of the CAST/Ei …

[HTML][HTML] Gains and losses: resilience to social defeat stress in adolescent female mice

AH Pantoja-Urbán, S Richer, A Mittermaier, M Giroux… - Biological …, 2024 - Elsevier
Background Adolescence is a unique period of psychosocial growth during which social
adversity can negatively influence mental health trajectories. Understanding how adolescent …

Maternal and umbilical cord concentrations of fentanyl after epidural analgesia for cesarean section

R Desprats, JC Dumas, M Giroux, G Campistron… - European Journal of …, 1991 - Elsevier
The maternal and umbilical concentrations of fentanyl were measured after epidural
analgesia for cesarean section, using a highly sensitive radioimmunoassay method. Sixteen …

Custom-built operant conditioning setup for calcium imaging and cognitive testing in freely moving mice

…, G Hernandez, AH Pantoja-Urban, M Giroux… - Eneuro, 2022 - eneuro.org
Operant chambers are widely used in animal research to study cognition, motivation, and
learning processes. Paired with the rapidly developing technologies for brain imaging and …

Relationship between insulin and Netrin-1/DCC guidance cue pathway regulation in the prefrontal cortex of rodents exposed to prenatal dietary restriction

…, MB Alves, JM Restrepo, M Giroux… - … Origins of Health and …, 2023 - cambridge.org
Fetal restriction (FR) alters insulin sensitivity, but it is unknown how the metabolic profile
associated with restriction affects development of the dopamine (DA) system and DA-related …