In the past decade, there has been renewed interest in immune/inflammatory changes and
their associated oxidative/nitrosative consequences as key pathophysiological mechanisms …

Background Cannabis use is associated with increased risk of later psychotic disorder but
whether it affects incidence of the disorder remains unclear. We aimed to identify patterns of …

Introduction Iatrogenic hyperprolactinaemia (IHPRL) has been more frequently related to some
antipsychotic drugs that provoke an intense blockade of dopamine D2 receptors. There is …

Exposures constitute a dense network of the environment: exposome. Here, we argue for
embracing the exposome paradigm to investigate the sum of nongenetic “risk” and show how …

BackgroundSome studies suggest individuals with schizophrenia have an increased risk of
diabetes prior to antipsychotic use. Small sample sizes and the potential for confounding by …

OBJECTIVE: The authors evaluated the comparative efficacy and safety of intramuscular
olanzapine, intramuscular haloperidol, and intramuscular placebo for the treatment of acute …

Importance Psychotic disorders contribute significantly to the global disease burden, yet the
latest international incidence study of psychotic disorders was conducted in the 1980s. …

Background: Resilience is a process that allows recovery from or adaptation to adversities.
The aim of this study was to evaluate state resilience during the COVID-19 pandemic in …

Background: Schizophrenia is a chronic syndrome of unknown etiology, predominantly
defined by signs of psychosis. The onset of the disorder occurs typically in late adolescence or …

Schizophrenia is a heritable complex phenotype associated with a background risk
involving multiple common genetic variants of small effect and a multitude of environmental …