Comparison of racemic ketamine and S-ketamine in treatment-resistant major depression: Report of two cases

R Paul, N Schaaff, F Padberg, HJ Möller… - The world journal of …, 2009 - Taylor & Francis
Recent studies with intravenous infusion of the NMDA receptor antagonist ketamine showed
robust and rapid antidepressant effects within hours after treatment. Ketamine is a racemic …

[I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects

W Koch, N Schaaff, G Pöpperl, C Mulert, G Juckel… - Journal of psychiatry and …, 2007 - jpn.ca
Objective: Serotonergic dysfunction is considered to be involved in the pathophysiology of
borderline personality disorder (BPD). The aim of this study was to investigate serotonin …

State of the art: treatment of bipolar disorders

E Severus, N Schaaff, HJ Möller - CNS neuroscience & …, 2012 - Wiley Online Library
Bipolar disorders are lifelong lasting affective disorders, with an episodic course of the illness
in most cases. The lifetime prevalence is around 2–5%, the illness usually appears in early …

Prediction of clinical response to antidepressants in patients with depression: neurophysiology in clinical practice

…, C Norra, G Leicht, S Karch, N Schaaff… - Clinical EEG and …, 2007 - journals.sagepub.com
Brain monoaminergic neurotransmission is involved in the pathophysiology of various
psychiatric disorders including depression. Reliable indicators of central monoaminergic activity …

Loudness dependence of auditory evoked potentials in patients with borderline personality disorder—Impact of psychopathology

N Schaaff, S Karch, F Segmiller, W Koch… - Psychiatry …, 2012 - Elsevier
Alterations of the central serotonergic system are considered to be involved in the
pathophysiology of borderline personality disorder (BPD). The loudness dependence of the N1/P2 …

[123I] ADAM brainstem binding correlates with the loudness dependence of auditory evoked potentials

O Pogarell, W Koch, N Schaaff, G Pöpperl… - European archives of …, 2007 - Springer
The in vivo assessment of brain serotonergic function might be of clinical relevance in
neuropsychiatry. The loudness dependence of auditory evoked potentials (LD) has been …

Structural brain changes in the emotional network in adult patients with ADHD compared to patients with major depression and healthy volunteers.

T Frodl, F Amico, J Stauber, N Schaaff… - European Child & …, 2010 - search.ebscohost.com
Introduction and objectives: The neurobiological underpinnings of comorbidity in adult ADHD
are unclear. To investigate whether adult ADHD patients may exhibit gray and/or white …

Use of clinical neurophysiology for the selection of medication in the treatment of major depressive disorder: the state of the evidence

AF Leuchter, IA Cook, A Hunter… - Clinical EEG and …, 2009 - journals.sagepub.com
Approximately 50% of patients with Major Depressive Disorder (MDD) respond to the first
antidepressant medication prescribed, and fewer than one-third experience remission of …

Hand-motor dysfunction in depression: characteristics and pharmacological effects

R Mergl, O Pogarell, G Juckel, J Rihl… - Clinical EEG and …, 2007 - journals.sagepub.com
Motor retardation is a relevant aspect of depression. Kinematic analysis of movements can
be applied to explore which type of motor dysfunction is associated with depression and to …

Loudness dependence of auditory-evoked potentials, a marker of central serotonergic activity, is affected by fasting and selective uptake of food

C Bamberg, V Flasbeck, G Juckel… - Clinical EEG and …, 2021 - journals.sagepub.com
Serotonin is an important neuromodulator involved in many physiological processes including
mood and satiety. In the brain, serotonin is manufactured from tryptophan, as serotonin …