Neuroleadership: Themes and limitations of an emerging interdisciplinary field
N Kuhlmann, CA Kadgien - Healthcare management forum, 2018 - journals.sagepub.com
The relationship between brain and behaviour has perplexed philosophers and scientists
since the time of the ancient Greeks. Recent technological advances have allowed …
since the time of the ancient Greeks. Recent technological advances have allowed …
[HTML][HTML] Chronic and acute manipulation of cortical glutamate transmission induces structural and synaptic changes in co-cultured striatal neurons
N Kuhlmann, M Wagner Valladolid… - Frontiers in Cellular …, 2021 - frontiersin.org
In contrast to the prenatal topographic development of sensory cortices, striatal circuit
organization is slow and requires the functional maturation of cortical and thalamic excitatory …
organization is slow and requires the functional maturation of cortical and thalamic excitatory …
[HTML][HTML] Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice
DA Beccano-Kelly, N Kuhlmann, I Tatarnikov… - Frontiers in cellular …, 2014 - frontiersin.org
Mutations in Leucine-Rich Repeat Kinase-2 (LRRK2) result in familial Parkinson's disease
and the G2019S mutation alone accounts for up to 30% in some ethnicities. Despite this, the …
and the G2019S mutation alone accounts for up to 30% in some ethnicities. Despite this, the …
Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice
…, SA Paschall, S Cataldi, SE MacIsaac, N Kuhlmann… - Elife, 2017 - elifesciences.org
10.7554/eLife.28377.001 LRRK2 mutations produce end-stage Parkinson’s disease (PD)
with reduced nigrostriatal dopamine, whereas, asymptomatic carriers have increased …
with reduced nigrostriatal dopamine, whereas, asymptomatic carriers have increased …
Chronic maternal hyperglycemia induced during mid-pregnancy in rats increases RAGE expression, augments hippocampal excitability, and alters behavior of the …
AR Chandna, N Kuhlmann, CA Bryce, Q Greba… - Neuroscience, 2015 - Elsevier
Maternal diabetes during pregnancy may increase the risk of neurodevelopmental disorders
in the offspring by increasing inflammation. A major source of inflammatory signaling …
in the offspring by increasing inflammation. A major source of inflammatory signaling …
[PDF][PDF] The X-linked intellectual disability gene Zdhhc9 is essential for dendrite outgrowth and inhibitory synapse formation
Palmitoylation is a reversible post-translational lipid modification that facilitates vesicular
transport and subcellular localization of modified proteins. This process is catalyzed by ZDHHC …
transport and subcellular localization of modified proteins. This process is catalyzed by ZDHHC …
[HTML][HTML] A critical LRRK at the synapse? The neurobiological function and pathophysiological dysfunction of LRRK2
N Kuhlmann, AJ Milnerwood - Frontiers in molecular neuroscience, 2020 - frontiersin.org
Since the discovery of LRRK2 mutations causal to Parkinson’s disease (PD) in the early
2000s, the LRRK2 protein has been implicated in a plethora of cellular processes in which …
2000s, the LRRK2 protein has been implicated in a plethora of cellular processes in which …
Chronic lithium treatment alters the excitatory/inhibitory balance of synaptic networks and reduces mGluR5–PKC signalling in mouse cortical neurons
…, A Ase, C Liao, A Kamesh, N Kuhlmann… - Journal of Psychiatry and …, 2021 - jpn.ca
Background: Bipolar disorder is characterized by cyclical alternation between mania and
depression, often comorbid with psychosis and suicide. Compared with other medications, the …
depression, often comorbid with psychosis and suicide. Compared with other medications, the …
[HTML][HTML] A neuroanatomical examination of embodied cognition: semantic generation to action-related stimuli
…, J Cummine, GE Sarty, N Kuhlmann… - Frontiers in Human …, 2012 - frontiersin.org
The theory of embodied cognition postulates that the brain represents semantic knowledge
as a function of the interaction between the body and the environment. The goal of our …
as a function of the interaction between the body and the environment. The goal of our …
Effects of improvisational dance movement therapy on balance and cognition in Parkinson's disease
M Fisher, N Kuhlmann, H Moulin, J Sack… - … Therapy in Geriatrics, 2020 - Taylor & Francis
Aims: This study examined the effects of group improvisational Dance Movement Therapy (DMT)
on balance and cognition in people with Parkinson’s disease. Methods: Ten community-…
on balance and cognition in people with Parkinson’s disease. Methods: Ten community-…
