Novelty exploration can enhance hippocampal plasticity in animals through dopaminergic
neuromodulation arising in the substantia nigra/ventral tegmental area (SN/VTA). This …

The dopaminergic midbrain, which comprises the substantia nigra and ventral tegmental area
(SN/VTA), plays a central role in reward processing. This region is also activated by novel …

Studies in humans and animals show that dopaminergic neuromodulation originating from
the substantia nigra/ventral tegmental area (SN/VTA) of the midbrain enhances hippocampal …

Recent data from animal studies raise the possibility that dopaminergic neuromodulation
promotes the encoding of novel stimuli. We investigated a possible role for the dopaminergic …

Invasive recording of dopamine neurons in the substantia nigra and ventral tegmental area (SN/VTA)
of behaving animals suggests a role for these neurons in reward learning and …

Working memory allows information from transient events to persist as active neural
representations [1] that can be used for goal-directed behaviors such as decision making and …

Activation of the hippocampus is required to encode memories for new events (or episodes).
Observations from animal studies suggest that, for these memories to persist beyond 4–6 h, …

In this functional magnetic resonance imaging (fMRI) study, we investigated the neural basis
of mental auditory imagery of familiar complex sounds that did not contain language or …

Recollection of contextual information represents the core of human recognition memory. It
has been associated with theta (4–8 Hz) power in electrophysiological recordings and, …

Reward representation in ventral striatum is boosted by perceptual novelty, although the
mechanism of this effect remains elusive. Animal studies indicate a functional loop ( Lisman and …