Context The monoamine theory of depression proposes that monoamine levels are lowered,
but there is no explanation for how monoamine loss occurs. Monoamine oxidase A (MAO-A…

Disturbed circadian rhythms have been observed in seasonal affective disorder (SAD). The
aim of this study was to further investigate this connection, and to test for potential …

Bright-light therapy (BLT) is established as the treatment of choice for seasonal affective
disorder/winter type (SAD). In the last two decades, the use of BLT has expanded beyond SAD: …

Context It is a common experience in temperate zones that individuals feel happier and more
energetic on bright and sunny days and many experience a decline in mood and energy …

Background Evidence suggests that serotonin transporter gene promoter polymorphism(5HTTLPR)–dependent
low transcriptional activity of the human serotonin transporter gene may …

BACKGROUND: The serotonin transporter (5-HTT)-linked polymorphic region (5-HTTLPR)
has two frequent alleles, designated long (L), and short (S). The S allele is associated with …

BackgroundThere is some evidence that natural levels of lithium in drinking water may have
a protective effect on suicide mortality.AimsTo evaluate the association between local …

Departments ofNeurology, Nuclear Medicine, and General Psychiatry, University of Vienna,
Vienna; Forschungszentrum Seibersdotf Seibersdorf,@ and Department ofNeurology, …

Importance It has been observed that suicidal behavior is influenced by sunshine and
follows a seasonal pattern. However, seasons bring about changes in several other …

Insufficient default mode network (DMN) suppression was linked to increased rumination in
symptomatic Major Depressive Disorder (MDD). Since rumination is known to predict relapse …