User profiles for Nikolai V. Malykhin

Nikolai Malykhin

Professor of Psychiatry and Neuroscience, University of Alberta
Verified email at ualberta.ca
Cited by 3582

Structural changes in the hippocampus in major depressive disorder: contributions of disease and treatment

NV Malykhin, R Carter, P Seres, NJ Coupland - Journal of Psychiatry and …, 2010 - jpn.ca
Background: Previous magnetic resonance imaging (MRI) studies of patients with major
depressive disorder (MDD) have consistently shown bilateral and unilateral reductions in …

Structural changes in hippocampal subfields in major depressive disorder: a high-field magnetic resonance imaging study

…, R Carter, P Seres, AH Wilman, NV Malykhin - Biological …, 2013 - Elsevier
BACKGROUND: Magnetic resonance imaging (MRI) has shown lower hippocampal volume
in major depressive disorder (MDD). Preclinical and postmortem studies show that chronic …

In vivo quantification of hippocampal subfields using 4.7 T fast spin echo imaging

NV Malykhin, RM Lebel, NJ Coupland, AH Wilman… - Neuroimage, 2010 - Elsevier
Several neuropsychiatric disorders involving hippocampal structural changes have been
studied extensively using volumetric magnetic resonance imaging (MRI). These studies have …

Three-dimensional volumetric analysis and reconstruction of amygdala and hippocampal head, body and tail

NV Malykhin, TP Bouchard, CJ Ogilvie… - Psychiatry Research …, 2007 - Elsevier
Volumetric changes in the amygdala and hippocampus are relevant to many disorders, but
their close proximity makes it difficult to separate these structures by magnetic resonance …

Differential vulnerability of hippocampal subfields and anteroposterior hippocampal subregions in healthy cognitive aging

NV Malykhin, Y Huang, S Hrybouski, F Olsen - Neurobiology of Aging, 2017 - Elsevier
In the present study, we investigated whether hippocampal subfields (cornu ammonis 1-3,
dentate gyrus, and subiculum) and anteroposterior hippocampal subregions (head, body, and …

Amygdala subnuclei response and connectivity during emotional processing

…, CA Baron, P Seres, C Beaulieu, F Olsen, NV Malykhin - Neuroimage, 2016 - Elsevier
The involvement of the human amygdala in emotion-related processing has been studied
using functional magnetic resonance imaging (fMRI) for many years. However, despite the …

Dentate gyrus volume and memory performance in major depressive disorder

…, E Fujiwara, R Carter, P Seres, NV Malykhin - Journal of affective …, 2015 - Elsevier
Background Magnetic resonance imaging (MRI) has shown lower hippocampal volume in
major depressive disorder (MDD). Patients with MDD have consistently demonstrated worse …

Aging hippocampus and amygdala

NV Malykhin, TP Bouchard, R Camicioli… - …, 2008 - journals.lww.com
Earlier studies suggest that the anterior hippocampus may show resilience to age-associated
volume loss. This study compared high-resolution magnetic resonance images obtained …

Fronto-limbic volumetric changes in major depressive disorder

NV Malykhin, R Carter, KM Hegadoren, P Seres… - Journal of affective …, 2012 - Elsevier
BACKGROUND: Fronto-limbic dysregulation in major depressive disorder (MDD) may be
influenced by early life stress and antidepressant treatment. The present structural MRI study …

Effects of cortisol on hippocampal subfields volumes and memory performance in healthy control subjects and patients with major depressive disorder

…, R Carter, E Fujiwara, P Seres, NV Malykhin - Journal of affective …, 2016 - Elsevier
Overactivity of the hypothalamic-pituitary-adrenal (HPA) axis in major depressive disorder (MDD)
is among the most consistently replicated biological findings in psychiatry. Magnetic …