This study investigated the respective roles of the hippocampus, the amygdala, and the dorsal
striatum in learning and memory. A standard set of experimental conditions for studying …

The present experiments were designed to examine the hypothesis that the mammalian
brain contains anatomically distinct memory systems. Rats with bilateral lesions of caudate …

A theory of multiple parallel memory systems in the brain of the rat is described. Each system
consists of a series of interconnected neural structures. The “central structures” of the three …

This experiment investigated the ability of rats withdorsal striatal or fornix damage to learn the
location of a visible platform in a water maze. We also assessed the animals' ability to find …

The effect of posttraining intracerebral injections of the indirect dopamine (DA) agonist d-amphetamine,
the direct D2 agonist LY 171555, and the direct D1 agonist SKF-38393 on the …

This review applies some new experimental findings and theoretical ideas about how reinforcers
act on the neural mechanisms of learning and memory to the problem of how addictive …

We investigated the effects of localized medial and lateral CPu lesions and fornix/fimbria
lesions on responses to a local cue and to behavior based on cognitive–spatial information in …

The dopamine D3 receptor is expressed primarily in regions of the brain that are thought to
influence motivation and motor functions. To specify in vivo D3 receptor function, we …

The histories of the terms “reward” and “reinforcement” are reviewed to show the difference
in their origins. Reward refers to the fact that certain environmental stimuli have the property …

Rats received injections of d-amphetamine sulphate (10ug in 0.5ul) in nucleus accumbens
and were placed into one of two (randomly assigned) distinctive environments. The next day …