Neurotensin is a brain and gastrointestinal peptide that fulfils many central and peripheral
functions through its interaction with specific receptors. Three subtypes of neurotensin …

Chemokines are not only found in the immune system or expressed in inflammatory conditions:
they are constitutively present in the brain in both glial cells and neurons. Recently, the …

Accumulating evidence supports a role of chemokines and their receptors in brain function.
Up to now scarce evidence has been given of the neuroanatomical distribution of chemokine …

The monocyte chemoattractant protein‐1 (MCP‐1/CCL2) and its receptor CCR2 are key
modulators of immune functions. In the nervous system, MCP‐1/CCL2 is implicated in …

CCL2 chemokine and its receptor CCR2 may contribute to neuropathic pain development.
We tested the hypothesis that injury to peripheral nerves triggers CCL2 release from afferents …

SR 142948A, 2-{[5-(2,6-dimethoxyphenyl)-1-(4-(N-(3-dimethylaminopropyl)-N-methylcarbamoyl)-2-isopropylphenyl)-1H-pyrazole-3-carbonyl]amino}adamantane-2-carboxylic
acid, …

In the CNS, immune‐like competent cells (microglia and astrocytes) were first described as
potential sites of chemokine synthesis, but more recent evidence has indicated that neurones …

Radioimmunoassayable neurotensin (R-NT) has been isolated from acid/acetone extracts of
50 kg of calf small intestine with an overall yield of approximately 15%. The concentration of …

A better understanding of the mechanisms linked to chemokine pronociceptive effects is
essential for the development of new strategies to better prevent and treat chronic pain. Among …

The stromal cell‐derived factor‐1 (SDF‐1)/CXCL12 and its receptor CXCR4 are key
modulators of immune functions. In the nervous system, SDF‐1/CXCL12 is crucial for neuronal …