User profiles for Paul D. Metzak

Paul Metzak

N3 Research Scientist, University of Calgary
Verified email at ucalgary.ca
Cited by 1295

Decreased efficiency of task-positive and task-negative networks during working memory in schizophrenia

PD Metzak, JD Riley, L Wang, JC Whitman… - Schizophrenia …, 2012 - academic.oup.com
Working memory (WM) is one of the most impaired cognitive processes in schizophrenia.
Functional magnetic resonance imaging (fMRI) studies in this area have typically found a …

Impaired efficiency of functional networks underlying episodic memory-for-context in schizophrenia

L Wang, PD Metzak, WG Honer… - Journal of …, 2010 - Soc Neuroscience
Memory for context and episodic memory have been identified as primary contributors to
cognitive impairments in schizophrenia. This study examined neural networks involved in …

Aberrant connectivity during self–other source monitoring in schizophrenia

L Wang, PD Metzak, TS Woodward - Schizophrenia research, 2011 - Elsevier
Numerous investigations into schizophrenia have reported impairment in self–other source
monitoring, and studies on healthy subjects have suggested that the medial prefrontal cortex (…

Hippocampal tail volume as a predictive biomarker of antidepressant treatment outcomes in patients with major depressive disorder: a CAN-BIND report

…, GB Hall, JK Harris, M Zamyadi, PD Metzak… - …, 2020 - nature.com
Finding a clinically useful neuroimaging biomarker that can predict treatment response in
patients with major depressive disorder (MDD) is challenging, in part because of poor …

Anterior cingulate cortex signals the requirement to break inertia when switching tasks: A study of the bivalency effect

TS Woodward, PD Metzak, B Meier, CB Holroyd - Neuroimage, 2008 - Elsevier
When switching tasks, if stimuli are presented that cue two of the tasks in the task set (ie,
bivalent stimuli), performance slowing is observed on all tasks, including those not cued by the …

Left-dominant temporal-frontal hypercoupling in schizophrenia patients with hallucinations during speech perception

KM Lavigne, LA Rapin, PD Metzak… - Schizophrenia …, 2015 - academic.oup.com
Background: Task-based functional neuroimaging studies of schizophrenia have not yet
replicated the increased coordinated hyperactivity in speech-related brain regions that is …

Testing a deep convolutional neural network for automated hippocampus segmentation in a longitudinal sample of healthy participants

…, AD Davis, GB Hall, JK Harris, M Zamyadi, PD Metzak… - NeuroImage, 2019 - Elsevier
Subtle changes in hippocampal volumes may occur during both physiological and
pathophysiological processes in the human brain. Assessing hippocampal volumes manually is a …

Epoch-specific functional networks involved in working memory

TS Woodward, E Feredoes, PD Metzak, Y Takane… - Neuroimage, 2013 - Elsevier
Working memory (WM) is not a unitary construct. There are distinct processes involved in
encoding information, maintaining it on-line, and using it to guide responses. The anatomical …

Functional brain networks underlying detection and integration of disconfirmatory evidence

KM Lavigne, PD Metzak, TS Woodward - Neuroimage, 2015 - Elsevier
Processing evidence that disconfirms a prior interpretation is a fundamental aspect of belief
revision, and has clear social and clinical relevance. This complex cognitive process …

Compensatory motor network connectivity is associated with motor sequence learning after subcortical stroke

KP Wadden, TS Woodward, PD Metzak… - Behavioural brain …, 2015 - Elsevier
Following stroke, functional networks reorganize and the brain demonstrates widespread
alterations in cortical activity. Implicit motor learning is preserved after stroke. However the …