Importance Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …

The aim of this study was to simulate the stress response in the periodontium of the maxillary
first molar to different moment to force ratios, and to determine the moment to force ratio for …

The purpose of the study was to use the finite element method to simulate the effect of alveolar
bone loss on orthodontically induced stress in the periodontal ligament of the maxillary …

Early response to antipsychotic medications is one of the most important determinants of
later symptomatic and functional outcomes in psychosis. Glutathione and glutamate have …

Glutamatergic dysfunction is implicated in schizophrenia pathoaetiology, but this may vary
in extent between patients. It is unclear whether inter-individual variability in glutamate is …

Background Functional dysconnection in schizophrenia is underwritten by a pathophysiology
of the glutamate neurotransmission that affects the excitation-inhibition balance in key …

Introduction Symptoms of schizophrenia are closely related to aberrant language comprehension
and production. Macroscopic brain changes seen in some patients with schizophrenia …

Oxidative stress plays a key role in the pathophysiology of schizophrenia. While free radicals
produced by glutamatergic excess and oxidative metabolism have damaging effects on …

Disrupted serotonergic and glutamatergic signaling interact and contribute to the pathophysiology
of schizophrenia, which is particularly relevant for the hippocampus where diverse …

Schizophrenia continues to be an illness with poor outcome. Most mechanistic changes
occur many years before the first episode of schizophrenia; these are not reversible after the …