Background Parkinson's disease is typically treated with oral dopamine replacement therapies;
however, long-term treatment leads to motor complications and, occasionally, impulse …

Acute stimulation of cardiac β1-adrenergic receptors (β1ARs) by norepinephrine represents
the strongest endogenous mechanism for increasing cardiac function, but long-term …

Rationale: Telomere length is considered a marker for biological aging. Chronic obstructive
pulmonary disease (COPD) may be associated with premature aging. Objectives: To test the …

Rationale: Chronic obstructive pulmonary disease (COPD) is associated with chronic
inflammation of unknown pathogenesis. Objectives: To investigate whether telomere dysfunction …

Background Pulmonary artery remodeling triggered by alveolar hypoxia is considered the
main mechanism of pulmonary hypertension (PH) in COPD patients. We hypothesized that the …

BACKGROUND: Strategies to reduce prostate-specific antigen (PSA)–driven prostate cancer
(PCa) overdiagnosis and overtreatment seem to be necessary. OBJECTIVE: To test the …

Aim The MITOCARE study evaluated the efficacy and safety of TRO40303 for the reduction
of reperfusion injury in patients undergoing revascularization for ST-elevation myocardial …

Aims Intracoronary administration of autologous bone marrow cells (BMCs) leads to a modest
improvement in cardiac function, but the effect on myocardial viability is unknown. The aim …

Objectives To test the sensitivity, specificity and accuracy of serum prostate‐specific antigen
isoform [‐2] proPSA ( p2PSA ), % p2PSA and the prostate health index ( PHI ), in men with a …

BACKGROUND: Prenatal exposure to viruses or parasites with tropism for the central
nervous system is one of the risk factors for psychotic disorders. However, the relationship …