n-3 Polyunsaturated fatty acids (PUFAs) inhibit the development of microvessels in mammary
tumors growing in mice. Human colorectal tumors produce vascular endothelial growth …

Parkinson's disease is associated with gastrointestinal motility abnormalities favoring the
occurrence of local infections. The aim of this study was to investigate whether small intestinal …

Purpose : In laboratory studies electromotive mitomycin C (MMC) demonstrated markedly
increased transport rates compared with passive transport. We performed a prospective study …

It has previously been shown that interleukin-1 (IL-1) directly stimulates the release of CRH-41
from rat hypothalamus in vitro, suggesting that cytokines may mediate the effects of …

Background Migraine is a complex, chronic, painful, neurovascular disorder characterized
by episodic activation of the trigeminal system. Increased levels of calcitonin gene-related …

Microglia and macrophages appear to be the most common cells in the GBM microenvironment.
In the present study we investigated the status of macrophages/microglia activation in …

Microglia, unique myeloid cells residing in the brain parenchyma, represent the first line of
immune defense within the central nervous system. In addition to their immune functions, …

Neuroinflammation plays a prominent role in the pathophysiology of several neurodegenerative
disorders, including Multiple Sclerosis. Reactive microglial cells are always found in …

Age-related macular degeneration (AMD) constitutes a prevalent, chronic, and progressive
retinal degenerative disease of the macula that affects elderly people and cause central …

Ipilimumab (Yervoy, developed by Medarex and Bristol-Myers Squibb) is a fully human
monoclonal IgG1κ antibody against the cytotoxic T-lymphocyte antigen-4 (CTLA-4), an immune-…