Molecular packing: another key point for the performance of organic and polymeric optoelectronic materials

Q Li, Z Li - Accounts of chemical research, 2020 - ACS Publications
Conspectus Optoelectronic material properties are governed by the whole collective of organic
moieties, and these aggregate states present the characteristic performance of extended …

Practical protocols for production of very high yields of recombinant proteins using Escherichia coli

…, V Murray, C Cui, Y Zhang, J Wang, Q Li - Protein …, 2009 - Wiley Online Library
The gram‐negative bacterium Escherichia coli offers a mean for rapid, high yield, and
economical production of recombinant proteins. However, high‐level production of functional …

[PDF][PDF] The impact of mutations in SARS-CoV-2 spike on viral infectivity and antigenicity

…, H Qin, M Wang, Q Lu, X Li, Q Sun, J Liu, L Zhang, X Li… - Cell, 2020 - cell.com
The spike protein of SARS-CoV-2 has been undergoing mutations and is highly glycosylated.
It is critically important to investigate the biological significance of these mutations. Here, …

[HTML][HTML] Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

…, F Jian, T Xiao, W Song, A Yisimayi, W Huang, Q Li… - Nature, 2022 - nature.com
The SARS-CoV-2 B.1.1.529 (Omicron) variant contains 15 mutations of the receptor-binding
domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies requires …

[HTML][HTML] BA. 2.12. 1, BA. 4 and BA. 5 escape antibodies elicited by Omicron infection

…, F Jian, W Song, T Xiao, L Wang, S Du, J Wang, Q Li… - Nature, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.
2.12. 1, BA. 4 and BA. 5 exhibit higher transmissibility than the BA. 2 lineage 1. The receptor …

Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2

J Nie, Q Li, J Wu, C Zhao, H Hao, H Liu… - Emerging microbes & …, 2020 - Taylor & Francis
Pseudoviruses are useful virological tools because of their safety and versatility, especially
for emerging and re-emerging viruses. Due to its high pathogenicity and infectivity and the …

[PDF][PDF] SARS-CoV-2 501Y. V2 variants lack higher infectivity but do have immune escape

Q Li, J Nie, J Wu, L Zhang, R Ding, H Wang, Y Zhang… - Cell, 2021 - cell.com
The 501Y.V2 variants of SARS-CoV-2 containing multiple mutations in spike are now dominant
in South Africa and are rapidly spreading to other countries. Here, experiments with 18 …

Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody

…, N Wang, J Nie, Z Cui, D Zhu, N Shaw, XF Li, Q Li… - Science, 2020 - science.org
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. …

[HTML][HTML] Quantification of SARS-CoV-2 neutralizing antibody by a pseudotyped virus-based assay

J Nie, Q Li, J Wu, C Zhao, H Hao, H Liu, L Zhang… - Nature protocols, 2020 - nature.com
Pseudotyped viruses are useful virological tools because of their safety and versatility. On
the basis of a vesicular stomatitis virus (VSV) pseudotyped virus production system, we …

[HTML][HTML] Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants

K Wang, Z Jia, L Bao, L Wang, L Cao, H Chi, Y Hu, Q Li… - Nature, 2022 - nature.com
Omicron (B.1.1.529), the most heavily mutated SARS-CoV-2 variant so far, is highly resistant
to neutralizing antibodies, raising concerns about the effectiveness of antibody therapies …