International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors

…, I Marshall, DM Smith, R Quirion, W Born, R Muff… - Pharmacological …, 2002 - ASPET
The calcitonin family of peptides comprises calcitonin, amylin, two calcitonin gene-related
peptides (CGRPs), and adrenomedullin. The first calcitonin receptor was cloned in 1991. Its …

XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors

…, HN Doods, H Herzog, D Larhammar, R Quirion… - Pharmacological …, 1998 - ASPET
… Species abbreviations are h for humans, m for mouse, r for rat, x for Xenopus laevis, z for
zebrafish, and Dm for Drosophila melanogaster. mGCRC is a murine orphan receptor. Figure …

Alzheimer's disease and the basal forebrain cholinergic system: relations to β-amyloid peptides, cognition, and treatment strategies

…, TJ Kornecook, S Bastianetto, R Quirion - Progress in neurobiology, 2002 - Elsevier
Alzheimer’s disease (AD) is the most common form of degenerative dementia and is
characterized by progressive impairment in cognitive function during mid- to late-adult life. Brains …

“APUD” Cells

FAO Mendelsohn, R Quirion, JM Saavedra - brain, 1984 - cell.com
Pearse’s ‘APUD” cell theory helps define the ontogeny and differentiation programs of small
polypeptide hormone-secreting cells of diverse tissue origins. Cells with such features may …

Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease.

J Poirier, MC Delisle, R Quirion… - Proceedings of the …, 1995 - National Acad Sciences
Apolipoprotein E (apoE) is critical in the modulation of cholesterol and phospholipid transport
between cells of different types. Human apoE is a polymorphic protein with three common …

Neuroanatomical localization, pharmacological characterization and functions of CGRP, related peptides and their receptors

D Van Rossum, UK Hanisch, R QUIRION - Neuroscience & Biobehavioral …, 1997 - Elsevier
… HANISCH AND R. QUIRION. Neuroanatomical localization, pharmacological characterization
and functions of CGRP, related peptides and their receptors. NEUROSCI BIOBEHAV REV …

Say NO to Alzheimer's disease: the putative links between nitric oxide and dementia of the Alzheimer's type

A Law, S Gauthier, R Quirion - Brain research reviews, 2001 - Elsevier
Alzheimer’s disease (AD) is the most common form of dementia, with progressive cognitive
deficits being the primary symptom. AD is neuropathologically characterized by amyloid and …

Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y …

…, R Quirion, L Caberlotto, R Rimondini… - Proceedings of the …, 2000 - National Acad Sciences
Exogenous neuropeptide Y (NPY) reduces experimental anxiety in a wide range of animal
models. The generation of an NPY-transgenic rat has provided a unique model to examine …

Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis

P Seeman, D Weinshenker, R Quirion… - Proceedings of the …, 2005 - National Acad Sciences
Dopamine supersensitivity occurs in schizophrenia and other psychoses, and after hippocampal
lesions, antipsychotics, ethanol, amphetamine, phencyclidine, gene knockouts of Dbh (…

The effects of chronic antidepressant treatment in an animal model of anxiety

…, B Suranyi-Cadotte, DH Aitken, R Quirion… - …, 1988 - Springer
We have examined the anxiolytic activity of acute and chronic antidepressant treatment in an
animal model of anxiety involving novelty-suppressed feeding. Rats were food deprived for …