Morphine produces analgesia at opiate receptors expressed in nociceptive circuits. μ, δ,
and κ opiate receptor subtypes are expressed in circuits that can modulate nociception and …

The brain vesicular monoamine transporter (VMAT2) pumps monoamine neurotransmitters
and Parkinsonism-inducing dopamine neurotoxins such as 1-methyl-4-phenyl-…

Thalamocortical neurons innervating the barrel cortex in neonatal rodents transiently store
serotonin (5-HT) in synaptic vesicles by expressing the plasma membrane serotonin …

Polygenic factors play important roles in animal models of substance abuse and susceptibility
to dopaminergic neurodegeneration. Genetic factors are also likely to contribute to the …

Cocaine blocks the normal role of the dopamine transporter (DAT) in terminating dopamine
signaling through molecular interactions that are only partially understood. Cocaine analog …

Repeated doses of cocaine or amphetamine lead to long-lasting behavioral manifestations
that include enhanced responses termed sensitization. Although biochemical mechanisms …

Although the prefrontal cortex (PFC) is usually associated with mediation of higher order
cognitive functions, it also influences affect and visceral function. These latter functions may, in …

In an extension of our previous work, an antibody directed against a peptide from the N‐terminal
region of DAT was used to localize specific dopamine transporter immunoreactivity (DAT…

Cocaine and methylphenidate block uptake by neuronal plasma membrane transporters for
dopamine, serotonin, and norepinephrine. Cocaine also blocks voltage-gated sodium …

… SLIPP GARY SMIRNOFF EILEEN S SMITH WESLEY I SMITH RICHARD SMOKTUNOWICZ
DAVID S. SOBIERAJ ADRIENNE MARSHA SOFFER PETER SPAMBANATO …