User profiles for Raphaël Chouinard-Watkins

Raphael Chouinard-Watkins

Postdoctoral fellow at University of Toronto
Verified email at usherbrooke.ca
Cited by 1557

[HTML][HTML] Brain docosahexaenoic acid uptake and metabolism

RJS Lacombe, R Chouinard-Watkins… - Molecular Aspects of …, 2018 - Elsevier
Docosahexaenoic acid (DHA) is the most abundant n-3 polyunsaturated fatty acid in the
brain where it serves to regulate several important processes and, in addition, serves as a …

[HTML][HTML] Docosahexaenoic and arachidonic acids as neuroprotective nutrients throughout the life cycle

…, F Echeverria, A Valenzuela, R Chouinard-Watkins… - Nutrients, 2021 - mdpi.com
The role of docosahexaenoic acid (DHA) and arachidonic acid (AA) in neurogenesis and
brain development throughout the life cycle is fundamental. DHA and AA are long-chain …

[HTML][HTML] Plasma incorporation, apparent retroconversion and β-oxidation of 13C-docosahexaenoic acid in the elderly

M Plourde, R Chouinard-Watkins, M Vandal… - Nutrition & …, 2011 - Springer
Background Higher fish or higher docosahexaenoic acid (DHA) intake normally correlates
positively with higher plasma DHA level, but recent evidence suggests that the positive …

Stimulation of mild, sustained ketonemia by medium-chain triacylglycerols in healthy humans: estimated potential contribution to brain energy metabolism

…, M Fortier, J Tremblay-Mercier, R Chouinard-Watkins… - Nutrition, 2013 - Elsevier
OBJECTIVE: In humans consuming a normal diet, we investigated 1) the capacity of a
medium-chain triacylglycerol (MCT) supplement to stimulate and sustain ketonemia, 2) 13 C-β-…

Protein concentrations and activities of fatty acid desaturase and elongase enzymes in liver, brain, testicle, and kidney from mice: Substrate dependency

…, G Cisbani, ME Smith, R ChouinardWatkins… - Biofactors, 2024 - Wiley Online Library
The synthesis rates of n‐3 and n‐6 polyunsaturated fatty acids (PUFAs) in rodents and humans
are not agreed upon and depend on substrate availability independently of the capacity …

[HTML][HTML] Impact of maternal obesity on the metabolism and bioavailability of polyunsaturated fatty acids during pregnancy and breastfeeding

…, Y Muñoz, M Ortiz, M Maliqueo, R Chouinard-Watkins… - Nutrients, 2020 - mdpi.com
Prenatal and postnatal development are closely related to healthy maternal conditions that
allow for the provision of all nutritional requirements to the offspring. In this regard, an …

[HTML][HTML] Fatty acid metabolism in carriers of apolipoprotein E epsilon 4 allele: is it contributing to higher risk of cognitive decline and coronary heart disease?

R Chouinard-Watkins, M Plourde - Nutrients, 2014 - mdpi.com
… -Santé for a PhD scholarship to Raphaël Chouinard-Watkins and a Junior 1 salary award to
… Mélanie Plourde and Raphaël Chouinard-Watkins contributed equally to the redaction and …

Disturbance in uniformly 13C-labelled DHA metabolism in elderly human subjects carrying the apoE ε4 allele

R Chouinard-Watkins, C Rioux-Perreault… - British journal of …, 2013 - cambridge.org
Carrying the apoE ε4 allele (E4+) is the most important genetic risk for Alzheimer's disease.
Unlike non-carriers (E4 − ), E4+ seem not to be protected against Alzheimer's disease when …

[PDF][PDF] The mitochondrial transacylase, tafazzin, regulates AML stemness by modulating intracellular levels of phospholipids

…, D Sharon, G Thomas, R Chouinard-Watkins… - Cell stem cell, 2019 - cell.com
Tafazzin (TAZ) is a mitochondrial transacylase that remodels the mitochondrial cardiolipin
into its mature form. Through a CRISPR screen, we identified TAZ as necessary for the growth …

Docosahexaenoic acid homeostasis, brain aging and Alzheimer's disease: Can we reconcile the evidence?

SC Cunnane, R Chouinard-Watkins… - … and Essential Fatty …, 2013 - Elsevier
A crossroads has been reached on research into docosahexaenoic acid (DHA) and Alzheimer's
disease (AD). On the one hand, several prospective observational studies now clearly …