Deletions of chromosome 18q are among the most common segmental aneusomies compatible
with life. The estimated frequency is approximately 1/40,000 live births [Cody JD, Pierce …

One of our primary goals is to help families who have a child with an 18q deletion anticipate
medical issues in order to optimize their child's medical care. To this end we have narrowed …

The clinical importance of social cognition is well acknowledged in patients with psychosis,
in particular those with first episode psychosis (FEP). Nevertheless, its brain substrates and …

The objective of this study was to assess the spectrum of growth abnormalities in children
with 18q deletions. The growth axis of 50 individuals with a cytogenetically and molecularly …

Purpose: To determine the size and parental origin of the deletion in individuals with 18p−
syndrome. Methods: Molecular and fluorescence in situ hybridization analyses of the …

Most individuals with constitutional deletions of chromosome 18q have developmental
delays, dysmyelination of the brain, and growth failure due to growth hormone deficiency. We …

Chromosome 18q deletions (18q−) are survivable autosomal deletions, having an estimated
incidence of one in 40,000 live births. Our long-term goals were to 1) comprehensively …

Deep vein thrombosis (DVT) and pulmonary embolism (PE) are relatively rare occurrences
in the pediatric population. However, DVT and PE are associated with significant morbidity …

The collagenase B type IV (Col4B) gene is highly expressed in the osteoclast, the primary
bone-resorbing cell. However, factors that regulate expression of the Col4B gene are not well …

Background: Recent reports have indicated that symptom exacerbation after a period of
improvement, referred to as relapse, in early-stage psychosis could result in brain changes and …