Ketamine as an antidepressant: overview of its mechanisms of action and potential predictive biomarkers

D Matveychuk, RK Thomas… - Therapeutic …, 2020 - journals.sagepub.com
Ketamine, a drug introduced in the 1960s as an anesthetic agent and still used for that
purpose, has garnered marked interest over the past two decades as an emerging treatment for …

Lactate in the brain: an update on its relevance to brain energy, neurons, glia and panic disorder

L Riske, RK Thomas, GB Baker… - Therapeutic advances …, 2017 - journals.sagepub.com
Lactate is considered an important metabolite in the human body, but there has been
considerable debate about its roles in brain function. Research in recent years has suggested that …

Esketamine for treatment resistant depression

J Swainson, RK Thomas, S Archer… - Expert review of …, 2019 - Taylor & Francis
Introduction: Treatment Resistant Depression (TRD) is a common and burdensome
condition with poor outcomes and few treatment options. Esketamine is the S-enantiomer of …

Rapid effectiveness of intravenous ketamine for ultraresistant depression in a clinical setting and evidence for baseline anhedonia and bipolarity as clinical predictors …

RK Thomas, G Baker, J Lind… - Journal of …, 2018 - journals.sagepub.com
Background: Intravenous ketamine has been established as an efficacious and safe treatment,
with transient effect, for treatment-resistant depression. However, the effectiveness of …

Adapting to the impact of COVID-19 on mental health: an international perspective

RK Thomas, R Suleman, M Mackay, L Hayer… - Journal of Psychiatry and …, 2020 - jpn.ca
The coronavirus disease 2019 (COVID-19) pandemic has affected the mental health of the
entire population and poses unique challenges to the delivery of psychiatric services. To best …

Treating electroconvulsive therapy–induced mania with more electroconvulsive therapy: Evidence for electroconvulsive therapy as the ultra-mood stabilizer

RK Thomas, PJ White, S Dursun - SAGE open medical case …, 2018 - journals.sagepub.com
Electroconvulsive therapy has been described as a mood stabilizer, as it is effective in all
stages of bipolar disorder. Electroconvulsive therapy–induced mania is a known and …

Perceptual distortions and delusional thinking following ketamine administration are related to increased pharmacological MRI signal changes in the parietal lobe

J Stone, V Kotoula, C Dietrich… - Journal of …, 2015 - journals.sagepub.com
Ketamine produces effects in healthy humans that resemble the positive, negative and
cognitive symptoms of schizophrenia. We investigated the effect of ketamine administration on …

Isotretinoin-induced psychotic episode in a 17-year-old adolescent male

B Elhusein, W Elkhaled… - … Open Medical Case …, 2020 - journals.sagepub.com
Isotretinoin, a synthetic vitamin A derivative, is primarily used in the management of severe
nodulocystic acne. Since its introduction, isotretinoin has been linked with various psychiatric …

A 7-year follow-up of antenatal depression treatment with cognitive behavioral therapy: A case report of maternal and child outcomes

LS Bleker, J Milgrom, AW Gemmill… - SAGE open medical …, 2019 - journals.sagepub.com
There are few studies of cognitive behavioral therapy for women with antenatal depression
including qualitative and quantitative data, and yet, individual cases can provide valuable …

Major depressive disorder with religious struggle and completed suicide after hair transplantation

ME Ceylan, B Önen Ünsalver… - SAGE open medical …, 2017 - journals.sagepub.com
Objectives: Psychological outcomes of aesthetic surgical procedures like hair transplantation
are mostly positive including decreased anxiety, depression and social phobia and …