User profiles for Robert K. McNamara
Robert K. McNamara, Ph.D.Professor of Psychiatry and Behavioral Neuroscience Verified email at uc.edu Cited by 12842 |
Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia
…, Y Xia, D Maciejewski, RK McNamara… - Proceedings of the …, 1998 - National Acad Sciences
A recently identified chemokine, fractalkine, is a member of the chemokine gene family, which
consists principally of secreted, proinflammatory molecules. Fractalkine is distinguished …
consists principally of secreted, proinflammatory molecules. Fractalkine is distinguished …
Role of omega-3 fatty acids in brain development and function: potential implications for the pathogenesis and prevention of psychopathology
RK McNamara, SE Carlson - Prostaglandins, Leukotrienes and Essential …, 2006 - Elsevier
The principle omega-3 fatty acid in brain, docosahexaenoic acid (DHA), accumulates in the
brain during perinatal cortical expansion and maturation. Animal studies have demonstrated …
brain during perinatal cortical expansion and maturation. Animal studies have demonstrated …
Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats
Neonatal maternal separation of rat pups leads to a stable stress hyper-responsive phenotype
characterized by increased basal levels of corticotropin releasing factor (CRF) mRNA in …
characterized by increased basal levels of corticotropin releasing factor (CRF) mRNA in …
The neuropharmacological and neurochemical basis of place learning in the Morris water maze
RK McNamara, RW Skelton - Brain Research Reviews, 1993 - Elsevier
The Morris water maze (MWM) offers several advantages over other methods of studying
the neurochemical basis of learning and memory, particularly with respect to its ability to …
the neurochemical basis of learning and memory, particularly with respect to its ability to …
Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression
MJ Detke, Y Lu, DJ Goldstein, RK McNamara… - Journal of psychiatric …, 2002 - Elsevier
Existing therapies for major depressive disorder (MDD) have either limited efficacy and/or
poor tolerability. The present study examined the effects of duloxetine, a potent and balanced …
poor tolerability. The present study examined the effects of duloxetine, a potent and balanced …
Duloxetine in the acute and long-term treatment of major depressive disorder: a placebo-and paroxetine-controlled trial
…, CG Wiltse, CH Mallinckrodt, RK McNamara… - European …, 2004 - Elsevier
Background: Duloxetine is a balanced and potent dual reuptake inhibitor of serotonin (5-HT)
and norepinephrine (NE) that has previously been shown to be effective in the acute …
and norepinephrine (NE) that has previously been shown to be effective in the acute …
Selective deficits in the omega-3 fatty acid docosahexaenoic acid in the postmortem orbitofrontal cortex of patients with major depressive disorder
RK McNamara, CG Hahn, R Jandacek, T Rider… - Biological …, 2007 - Elsevier
BACKGROUND: Epidemiological surveys and peripheral tissue (red blood cells/plasma)
fatty acid composition studies suggest that omega-3 fatty acid deficiency is associated with …
fatty acid composition studies suggest that omega-3 fatty acid deficiency is associated with …
[HTML][HTML] Docosahexaenoic acid supplementation increases prefrontal cortex activation during sustained attention in healthy boys: a placebo-controlled, dose-ranging …
RK McNamara, J Able, R Jandacek, T Rider… - The American journal of …, 2010 - Elsevier
Background: Emerging evidence suggests that docosahexaenoic acid (DHA, 22:6n−3), the
principal omega-3 (n−3) fatty acid in brain gray matter, positively regulates cortical metabolic …
principal omega-3 (n−3) fatty acid in brain gray matter, positively regulates cortical metabolic …
Neuroprogression in bipolar disorder
MR Schneider, MP DelBello, RK McNamara… - Bipolar …, 2012 - Wiley Online Library
Schneider MR, DelBello MP, McNamara RK, Strakowski SM, Adler CM. Neuroprogression
in bipolar disorder. Bipolar Disord 2012: 14: 356–374. © 2012 The Authors. Journal …
in bipolar disorder. Bipolar Disord 2012: 14: 356–374. © 2012 The Authors. Journal …
International society for nutritional psychiatry research practice guidelines for omega-3 fatty acids in the treatment of major depressive disorder
Major depressive disorder (MDD) is a complex mental illness with unmet therapeutic needs.
The antidepressant effects of ω–3 polyunsaturated fatty acids (n–3 PUFAs) have been …
The antidepressant effects of ω–3 polyunsaturated fatty acids (n–3 PUFAs) have been …