User profiles for Robert W. McCarley

Robert W. McCarley

Professor of Psychiatry, Harvard Medical School
Verified email at hms.harvard.edu
Cited by 86795

A review of MRI findings in schizophrenia

…, CC Dickey, M Frumin, RW McCarley - Schizophrenia research, 2001 - Elsevier
After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both : Kraepelin, E., 1919/1971. Dementia praecox. …

Adenosine: a mediator of the sleep-inducing effects of prolonged wakefulness

…, M Thakkar, AA Bjørkum, RW Greene, RW McCarley - Science, 1997 - science.org
Both subjective and electroencephalographic arousal diminish as a function of the duration
of prior wakefulness. Data reported here suggest that the major criteria for a neural sleep …

Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups

JA Hobson, RW McCarley, PW Wyzinski - Science, 1975 - science.org
During the sleep cycle in cats, neurons localized to the posterolateral pole of the nucleus
locus coeruleus and the nucleus subcoeruleus undergo discharge rate changes that are the …

Control of sleep and wakefulness

…, RE Strecker, RW McCarley - Physiological …, 2012 - journals.physiology.org
This review summarizes the brain mechanisms controlling sleep and wakefulness. Wakefulness
promoting systems cause low-voltage, fast activity in the electroencephalogram (EEG). …

Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia

…, SV Faraone, RW McCarley… - Proceedings of the …, 2009 - National Acad Sciences
We examined the status of the neural network mediating the default mode of brain function,
which typically exhibits greater activation during rest than during task, in patients in the early …

[BOOK][B] Brainstem control of wakefulness and sleep

MM Steriade, RW McCarley - 2013 - books.google.com
… Copyright is not claimed in those portions of the volume written by Robert W. McCarley in his
… S, EEG-synchronized sleep; W, waking; SW and WS, transitional periods from S to W and …

The brain as a dream state generator: an activation-synthesis hypothesis of the dream process.

JA Hobson, RW McCarley - The American journal of psychiatry, 1977 - europepmc.org
Recent research in the neurobiology of dreaming sleep provides new evidence for possible
structural and functional substrates of formal aspects of the dream process. The data …

[HTML][HTML] Abnormalities of the left temporal lobe and thought disorder in schizophrenia: a quantitative magnetic resonance imaging study

…, D Metcalf, M Coleman, RW McCarley - … England Journal of …, 1992 - Mass Medical Soc
Background. Data from postmortem, CT, and magnetic resonance imaging (MRI) studies
indicate that patients with schizophrenia may have anatomical abnormalities of the left temporal …

Magnetic resonance imaging study of hippocampal volume in chronic, combat-related posttraumatic stress disorder

…, SP Orr, R Kikinis, FA Jolesz, RW McCarley… - Biological …, 1996 - Elsevier
This study used quantitative volumetric magnetic resonance imaging techniques to explore
the neuroanatomic correlates of chronic, combat-related posttraumatic stress disorder (PTSD…

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

…, J Mallet, M Mattheisen, M Mattingsdal, RW McCarley… - Nature …, 2017 - nature.com
Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …