The clinical characterization of the patient with primary psychosis aimed at personalization of management

…, V Peralta, G Thornicroft, R van Winkel… - World …, 2021 - Wiley Online Library
The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second‐…

Metabolic and cardiovascular adverse effects associated with antipsychotic drugs

M De Hert, J Detraux, R Van Winkel, W Yu… - Nature Reviews …, 2012 - nature.com
Antipsychotic medications can induce cardiovascular and metabolic abnormalities (such as
obesity, hyperglycemia, dyslipidemia and the metabolic syndrome) that are associated with …

Prevalence of metabolic syndrome and metabolic abnormalities in schizophrenia and related disorders—a systematic review and meta-analysis

…, D Vancampfort, K Sweers, R van Winkel… - Schizophrenia …, 2013 - academic.oup.com
Individuals with schizophrenia have high levels of medical comorbidity and cardiovascular
risk factors. The presence of 3 or more specific factors is indicative of metabolic syndrome, …

[HTML][HTML] Metabolic syndrome in people with schizophrenia: a review

…, V Schreurs, D Vancampfort, R Van Winkel - World …, 2009 - ncbi.nlm.nih.gov
Metabolic syndrome and other cardiovascular risk factors are highly prevalent in people with
schizophrenia. Patients are at risk for premature mortality and overall have limited access to …

Psychosocial stress and psychosis. A review of the neurobiological mechanisms and the evidence for gene-stress interaction

R van Winkel, NC Stefanis… - Schizophrenia …, 2008 - academic.oup.com
This article presents evidence suggesting that psychosocial stress may increase risk for
psychosis, especially in the case of cumulative exposure. A heuristically useful framework to …

Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication

MA De Hert, R van Winkel, D Van Eyck… - Schizophrenia …, 2006 - Elsevier
The presence of the metabolic syndrome is an important risk factor for cardiovascular
disease and diabetes. There are limited data on the prevalence of the metabolic syndrome in …

Typical and atypical antipsychotics differentially affect long-term incidence rates of the metabolic syndrome in first-episode patients with schizophrenia: a retrospective …

…, A Scheen, J Peuskens, R van Winkel - Schizophrenia …, 2008 - Elsevier
The presence of the metabolic syndrome (MetS) is an important risk factor for cardiovascular
disease and diabetes. There are limited data on the prevalence of MetS in patients with …

[HTML][HTML] Prevalence of diabetes, metabolic syndrome and metabolic abnormalities in schizophrenia over the course of the illness: a cross-sectional study

M De Hert, R van Winkel, D Van Eyck… - Clinical Practice and …, 2006 - Springer
Background Patients with schizophrenia are at high risk of developing metabolic
abnormalities. Method A prospective study focusing on metabolic disturbances in patients with …

Prevalence of diabetes and the metabolic syndrome in a sample of patients with bipolar disorder

R Van Winkel, M De Hert, D Van Eyck… - Bipolar …, 2008 - Wiley Online Library
Objectives: The presence of metabolic abnormalities is an important risk factor for
cardiovascular disease and diabetes. There are limited data on the prevalence of the metabolic …

Guidelines for screening and monitoring of cardiometabolic risk in schizophrenia: systematic evaluation

…, J Peuskens, K Sweers, R van Winkel… - The British Journal of …, 2011 - cambridge.org
BackgroundMetabolic and cardiovascular health problems have become a major focus for
clinical care and research in schizophrenia.AimsTo evaluate the content and quality of …