Different types of stress play important roles in the onset and modulation of irritable bowel
syndrome (IBS) symptoms. The physiological effects of psychological and physical stressors …

This study investigated the combined effect of neonatal maternal separation and acute
psychological stress on pain responses in adult rats. Long-Evans dams and their male pups were …

Background & Aims: N-methyl-d-aspartate (NMDA) receptors are ligand-gated ion channels
that have an important role in long-term potentiation and memory processing in the central …

The present study examined the effects of colonic inflammation on reflex responses to colorectal
distension (CRD) in awake rats. Visceromotor responses (VMR) to CRD were recorded …

In rodents, maternal pup interactions play an important role in programming the stress
responsiveness of the adult organism. The aims of this study were 1) to determine the effect of …

… SV Coutinho1, … Coutinho SV, Plotsky PM, Sablad M, et al. Neonatal maternal separation
alters stress-induced responses to viscerosomatic nociceptive stimuli in rat. Am J Physiol …

The present study was undertaken to examine the involvement of descending pain modulatory
systems from the brainstem rostral ventromedial medulla (RVM) in modulating visceral …

Abdominal contractions are a viscerosomatic reflex response to noxious colorectal irritation
in rats. In this study we characterize the modulating effect of chemical and mechanical …

We have recently reported a model of secondary hyperalgesia in which facilitation of the
thermal nociceptive tail-flick reflex following topical mustard oil is largely dependent on …

This study aimed to characterize the role of the neuropeptide calcitonin gene‐related
peptide (CGRP) in the development of mechanically induced visceral hyperalgesia. Tonic …