In this work, we review the studies of oxidative stress markers, showing association with the
pathophysiology of bipolar disorder (BD). BD is a prevalent, chronic and highly disabling …

Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that
alternate between mania and hypomania or between depression and mixed states, often …

Cannabidiol (CBD), a Cannabis sativa constituent, may present a pharmacological profile
similar to mood stabilizing drugs, in addition to anti-oxidative and neuroprotective properties. …

Ketamine is a non-competitive antagonist to the phencyclidine site of N-methyl-d-aspartate (NMDA)
receptor. Clinical findings point to a rapid onset of action for ketamine on the …

Major depression is characterized for symptoms at the psychological, behavioral and
physiological levels. The chronic mild stress model has been used as an animal model of …

Objective: Previous studies have suggested that oxidative stress may play a role in the
pathophysiology of bipolar disorder (BD). Moreover, recent studies indicate that lithium and …

Several studies have supported the idea that ionotropic glutamate N-methyl-d-aspartate
receptor (NMDA) is an important player in the etiology of psychopathologies, such as anxiety …

There is an emerging body of data suggesting that mood disorders are associated with
decreased brain-derived neurotrophic factor (BDNF). The present study aims to investigate the …

Major depression is a common, serious and recurrent disorder, characterized by symptoms
at the psychological, behavioral and physiological levels. Recent studies have suggested …

Bipolar disorder (BD) has been previously associated with accelerated aging; yet, the
mechanisms underlying this association are largely unknown. The epigenetic clock has been …