The zebrafish, Danio rerio, has been established as an excellent vertebrate model for the
study of developmental biology and gene function. It also has proven to be a valuable model to …

Mutations in the human PTEN‐induced kinase 1 (PINK1) gene are linked to recessive
familial Parkinson’s disease. Animal models of altered PINK1 function vary greatly in their …

Biallelic pathogenic variants in PLPBP (formerly called PROSC) have recently been shown
to cause a novel form of vitamin B6-dependent epilepsy, the pathophysiological basis of …

Spontaneous intracranial hemorrhage is a debilitating form of stroke, often leading to death
or permanent cognitive impairment. Many of the causative genes and the underlying …

To determine the impact of a controlled loss of dopaminergic neurons on locomotor function,
we generated transgenic zebrafish, Tg(dat: CFP ‐ NTR ), expressing a cyan fluorescent …

Background: The number of people with cognitive deficits and diseases, such as stroke,
dementia, or attention-deficit/hyperactivity disorder, is rising due to an aging, or in the case of …

Literature highlights the long-term effects of bullying and interpersonal cruelty, including
symptoms of trauma and shame. Although scholars have encouraged the development of …

Genetic mutations and environmental toxins are known to affect mitochondrial health and have
been implicated in the progressive degeneration of dopaminergic neurons in Parkinson's …

The pathogenesis of esophageal squamous papilloma is not known, but chronic mucosal
irritation and infection with human papillomavirus are two proposed etiologies. To investigate …

We have examined the pattern of expression of the homeo box-containing gene En-2 during
mouse embryogenesis using in situ hybridization. Transcripts were first detected in the …