Membrane microparticles are submicron fragments of membrane shed into extracellular space
from cells under conditions of stress/injury. They may be distinguished from other classes …

Spreading depression (SD) is a self-propagating wave of neuronal and glial depolarization
that may occur in virtually any gray matter region in the brain. One consequence of SD is an …

Cortical Spreading Depression (CSD) is a well-studied model of preconditioning that provides
a high degree of tolerance to a subsequent ischemic event in the brain. The present study …

Functional polymeric coatings have rapidly become one of the most efficient strategies to
endow biomaterials with enhanced bioactive properties. Among the bio-inspired polymers …

Numbers of circulating microparticles (MPs) are elevated in a variety of cardiovascular disorders,
and recent studies indicate that they are involved in inflammatory intercellular signaling…

Cerebral small vessel disease (CSVD) is a pathological process leading to lacunar infarcts,
leukoaraiosis and cerebral microbleeds. Dysfunction of the blood brain barrier (BBB) has …

This study examined the impact of corticotropin-releasing hormone type 1 receptor (CRHR1)
blockade using Antalarmin (ANT) on the expression of markers of neuroplasticity and …

Activation of peroxisome proliferator-activated receptor-γ (PPARγ) signaling after stroke may
reduce brain injury, but this effect will depend on the levels of receptor and cofactors. Here, …

Extracellular ATP is elevated by transient ischemia and is a potent signaling molecule in the
central nervous system. ATP promotes neuron survival from serum starvation by activating …

Circulating microparticles (MPs) are involved in many physiological processes and
numbers are increased in a variety of cardiovascular disorders. The present aims were to …