Pigment epithelium-derived factor (PEDF) is a multifunctional protein with neurotrophic, anti-oxidative,
and anti-inflammatory properties. It is also one of the most potent endogenous …

Focal adhesion kinase ( FAK ) controls adhesion‐dependent cell motility, survival, and
proliferation. FAK has kinase‐dependent and kinase‐independent functions, both of which play …

The constant heavy chain (CH1) domain affects antibody affinity and fine specificity, challenging
the paradigm that only variable regions contribute to antigen binding. To investigate the …

Antimicrobial peptides (AMPs) are promising drugs to kill resistant pathogens. In contrast to
bacteria, protozoan parasites, such as Leishmania, were little studied. Therefore, the …

POU1F1, a pituitary-specific POU-homeo domain transcription factor, plays an essential role
in the specification of the somatotroph, lactotroph and thyrotroph lineages and in the …

Collagen Q (ColQ) is a nonfibrillar collagen that plays a crucial role at the vertebrate
neuromuscular junction (NMJ) by anchoring acetylcholinesterase to the synapse. ColQ also …

Abstract Design of new osteoinductive biomaterials to reproduce an optimized physiological
environment capable of recruiting stem cells and instructing their fate towards the …

Monocytes are considered crucial actors of inflammation in sickle cell disease (SCD), being
responsible for an increased production of proinflammatory cytokines such as tumor …

Semen is an important vector for sexual HIV-1 transmission. Although CXCR4-tropic (X4)
HIV-1 may be present in semen, almost exclusively CCR5-tropic (R5) HIV-1 causes systemic …

Hybrid nanostructures are constructed by the direct coupling of fluorescent quantum dots and
plasmonic gold nanoparticles. Self-assembly is directed by the strong affinity between two …