Background Essential tremor is the most common movement disorder and is often refractory
to medical treatment. Surgical therapies, using lesioning and deep brain stimulation in the …

Background Deep Brain Stimulation (DBS) is thought to improve the symptoms of selected
neurological disorders by modulating activity within dysfunctional brain circuits. To date, there …

DBS is now an established symptomatic treatment modality for Parkinson's disease and
other movement disorders. Future work will undoubtedly involve establishing new indications …

Objective Refractory psychiatric disease is a major cause of morbidity and mortality worldwide,
and there is a great need for new treatments. In the last decade, investigators piloted …

INTRODUCTION: Recent developments in optical science and image processing have
miniaturized the components required for confocal microscopy. Clinical confocal imaging …

Objectives: Glioblastomas are aggressive primary brain cancers that are characterized by
extensive infiltration into the brain and are highly resistant to treatment. Through mathematical …

Background Chronic high-frequency electrical deep brain stimulation (DBS) of the subcallosal
cingulate region is currently being investigated clinically as a therapy for treatment of …

Figure 1:(A) Transcranial magnetic stimulation is thought to produce durable changes in
synaptic strength via the NMDA-receptor–dependent mechanisms of long-term potentiation and …

During the “DBS Canada Day” symposium held in Toronto July 4-5, 2014, the scientific
committee invited experts to discuss three main questions on target selection for deep brain …

OBJECTIVE The aim of this study was to evaluate the safety of 3-T MRI in patients with
implanted deep brain stimulation (DBS) systems. METHODS This study was performed in 2 …