Adults with type 2 diabetes are at an increased risk of developing certain brain or mental
disorders, including stroke, dementia, and depression. Although these disorders are not usually …

Arterial stiffness may be a cause of cerebral small vessel disease and cognitive impairment.
We therefore performed a systematic review and meta-analysis of studies on the association …

MRI features of cerebral small vessel disease (CSVD), ie white matter hyperintensities, lacunes,
microbleeds, perivascular spaces, and cerebral atrophy, may be associated with clinical …

Objectives : This study sought to investigate the association of local and segmental arterial
stiffness with incident cardiovascular events and all-cause mortality. Background : The …

Background : Carotid stiffening is considered a key element in the pathogenesis of stroke.
However, results of studies evaluating the association between carotid stiffness and incident …

Climie et al Macrovasculature and Microvasculature in HTN and T2D 1139 million global
disability-adjusted life years, an increase of 11.7% from 2005. 9 Because hypertension rarely …

Objective: The vascular depression hypothesis postulates that cerebral small vessel disease
(CSVD) leads to depressive symptoms by disruption of brain structures involved in mood …

AIMS: We evaluated the associations of diabetic complications and underlying pathology
with daily walking activity in type 2 diabetic patients without manifest mobility limitations. …

Diabetes mellitus imposes a significant and increasing burden on society, with major
consequences for human health, welfare and the economy worldwide. Persons with diabetes …

In the pathogenesis of cardiovascular events, interaction between risk factors has seldom
been identified. However, endothelial dysfunction on the one hand and type 2 diabetes mellitus…