Although endocannabinoids constitute one of the first lines of defense against pain, the
anatomical locus and the precise receptor mechanisms underlying cannabinergic modulation of …

BACKGROUND: Oxytocin (OT) has been suggested as a treatment to improve social behavior
in autistic patients. Accordingly, the OT (Oxt −/− ) and the OT receptor null mice (Oxtr −/− ) …

Few and often contradictory reports exist on the long-term neurobiological consequences of
cannabinoid consumption in adolescents. The endocannabinoid system plays an important …

Marijuana and hashish are the illicit drugs most frequently used by human adolescents.
Given the continued neurodevelopment throughout adolescence, adolescents may be more …

Cannabis is one of the most widely used illicit drugs among adolescents, and most users
first experiment with it in adolescence. Adolescence is a critical phase for brain development, …

In the present study we explored with a multidisciplinary approach, the role of anandamide (AEA)
in the modulation of anxiety behavior at the level of the prefrontal cortex (PFC). Low …

We evaluated the ability of cannabidiol (CBD) to impair the migration of tumor cells stimulated
by conditioned medium. CBD caused concentration‐dependent inhibition of the migration …

There is a general consensus that the effects of cannabinoid agonists on anxiety seem to be
biphasic, with low doses being anxiolytic and high doses ineffective or possibly anxiogenic. …

Despite the increasing use of cannabis among adolescents, there are little and often
contradictory studies on the long-term neurobiological consequences of cannabis consumption in …

The present review summarizes the latest information on the role and the pharmacological
modulation of the endocannabinoid system in mood disorders and its potential implication in …