Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease

R De la Fuente-Fernández, TJ Ruth, V Sossi… - Science, 2001 - science.org
The power of placebos has long been recognized for improving numerous medical
conditions such as Parkinson's disease (PD). Little is known, however, about the mechanism …

In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease

CS Lee, A Samii, V Sossi, TJ Ruth… - Annals of Neurology …, 2000 - Wiley Online Library
Clinical symptoms of Parkinson's disease (PD) do not manifest until dopamine (DA)
neuronal loss reaches a symptomatic threshold. To explore the mechanisms of functional …

Studies of the Uptake of Nitrate in Barley: I. Kinetics of 13NO3 Influx

MY Siddiqi, ADM Glass, TJ Ruth, TW Rufty Jr - Plant physiology, 1990 - academic.oup.com
13 NO 3 − was used to investigate patterns of NO 3 − influx into roots of barley plants (Hordeum
vulgare L. cv Klondike) previously grown with (`induced') or without (`uninduced') a …

Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias

…, Z Huang, S Furtado, JQ Lu, DB Calne, TJ Ruth… - Brain, 2004 - academic.oup.com
Peak-dose dyskinesias are abnormal movements that usually occur 1 h after oral
administration of levodopa, and often complicate chronic treatment of Parkinson's disease. We …

Ammonium uptake by rice roots (II. Kinetics of 13NH4+ influx across the plasmalemma)

MY Wang, MY Siddiqi, TJ Ruth, ADM Glass - Plant physiology, 1993 - academic.oup.com
Short-term influxes of 13NH4+ were measured in intact roots of 3-week-old rice (Oryza
sativa L. cv M202) seedlings that were hydroponically grown at 2, 100, or 1000 [mu]M NH4+. …

Positron emission tomography after MPTP: observations relating to the cause of Parkinson's disease

…, JW Langston, WRW Martin, AJ Stoessl, TJ Ruth… - Nature, 1985 - nature.com
The dopa analogue 6-fluorodopa (6-FD) used with positron emission tomography (PET) allows
in vivo visualization of dopamine and its metabolites in nigrostriatal nerve endings 1 . We …

Plankton copper requirements and uptake in the subarctic Northeast Pacific Ocean

…, JT Cullen, WK Johnson, K Gagnon, TJ Ruth… - Deep Sea Research …, 2009 - Elsevier
We undertook the first measurements of metabolic Cu requirements (net Cu:C assimilation
ratios) and steady-state Cu uptake rates (ρCu ss ) of natural plankton assemblages in the …

The shortage of technetium-99m and possible solutions

TJ Ruth - Annual Review of Nuclear and Particle Science, 2020 - annualreviews.org
Following a major shortage of 99 Mo in the 2009–2010 period, concern grew that the aging
reactor production facilities needed to be replaced. Most producers were using highly …

An automated module for the separation and purification of cyclotron-produced 99mTcO4−

…, J Wilson, SA McQuarrie, W English, TJ Ruth… - Nuclear medicine and …, 2012 - Elsevier
INTRODUCTION: The shortage of reactor-produced molybdenum-99 ( 99 Mo, t ½ =66 h)
has renewed interest in alternative production methods of its daughter isotope, technetium-99m …

The effect of LRRK2 mutations on the cholinergic system in manifest and premanifest stages of Parkinson's disease: a cross-sectional PET study

…, ZK Wszolek, MJ McKeown, MJ Adam, TJ Ruth… - The Lancet …, 2018 - thelancet.com
Background Markers of neuroinflammation are increased in some patients with LRRK2
Parkinson's disease compared with individuals with idiopathic Parkinson's disease, suggesting …