As we grow older, we may grow wiser, but we can also experience memory loss and cognitive
slowing that can interfere with our daily routines. The cognitive neuroscience of human …

Amyloid deposition is present in 20–50% of nondemented older adults yet the functional
consequences remain unclear. The current study found that amyloid accumulation is correlated …

Recent evidence suggests that some brain areas act as hubs interconnecting distinct,
functionally specialized systems. These nexuses are intriguing because of their potential role in …

Objective: We conducted a meta-analysis of relationships between amyloid burden and
cognition in cognitively normal, older adult humans. Methods: Methods of assessing amyloid …

Importance Positron emission tomography (PET) imaging now allows in vivo visualization of
both neuropathologic hallmarks of Alzheimer disease (AD): amyloid-β (Aβ) plaques and tau …

Importance Assessing the ability of Alzheimer disease neuroimaging markers to predict
short-term cognitive decline among clinically normal (CN) individuals is critical for upcoming …

The authors investigated the distinctiveness and interrelationships among visuospatial and
verbal memory processes in short-term, working, and long-term memories in 345 adults. …

Resting state functional connectivity MRI (fcMRI) is widely used to investigate brain networks
that exhibit correlated fluctuations. While fcMRI does not provide direct measurement of …

Objectives Amyloid‐beta (Aβ) and tau pathologies are commonly observed among clinically
normal older individuals at postmortem and can now be detected with in vivo neuroimaging. …

Alzheimer's disease (AD) has been associated with functional alterations in a distributed
network of brain regions linked to memory function, with a recent focus on the cortical regions …