Depression induces bone loss through stimulation of the sympathetic nervous system
…, J Tam, V Trembovler, V Csernus… - Proceedings of the …, 2006 - National Acad Sciences
Major depression is associated with low bone mass and increased incidence of osteoporotic
fractures. However, causality between depression and bone loss has not been established. …
fractures. However, causality between depression and bone loss has not been established. …
Synthesis and biological evaluation of cytotoxic analogs of somatostatin containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin
…, P Armatis, RZ Cai, V Csernus… - Proceedings of the …, 1998 - National Acad Sciences
To create cytotoxic hybrid analogs of somatostatin (SST), octapeptides RC-160 (d-Phe-C \documentclass[12pt]{minimal}
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Urocortinergic neurons respond in a differentiated manner to various acute stressors in the Edinger‐Westphal nucleus in the rat
B Gaszner, V Csernus, T Kozicz - Journal of Comparative …, 2004 - Wiley Online Library
Corticotropin‐releasing factor (CRF) was implicated as being a major contributor to the
neurochemically mediated central regulation of stress response; however, an increasing body of …
neurochemically mediated central regulation of stress response; however, an increasing body of …
Expression of growth hormone-releasing hormone (GHRH) messenger ribonucleic acid and the presence of biologically active GHRH in human breast, endometrial …
Z Kahán, JM Arencibia, VJ Csernus… - The Journal of …, 1999 - academic.oup.com
GHRH is produced in a variety of extrahypothalamic tissues, including some neoplasms. We
have previously reported that GHRH antagonists can inhibit the growth of various human …
have previously reported that GHRH antagonists can inhibit the growth of various human …
Synthesis and biological evaluation of antagonists of growth hormone-releasing hormone with high and protracted in vivo activities
JL Varga, AV Schally, VJ Csernus… - Proceedings of the …, 1999 - National Acad Sciences
Some antagonists of human growth hormone-releasing hormone (hGH-RH) synthesized
previously were shown to inhibit in vivo proliferation of various human cancers in nude mice. …
previously were shown to inhibit in vivo proliferation of various human cancers in nude mice. …
Altered expression patterns of clock gene mRNAs and clock proteins in human skin tumors
…, R Keszthelyi, G Szekeres, Z Battyáni, V Csernus… - Tumor Biology, 2013 - Springer
The majority of our genes may be regulated in a daily rhythm, including the genes for cell
cycle control. Epidemiological and genetic evidences suggest that disruption of circadian …
cycle control. Epidemiological and genetic evidences suggest that disruption of circadian …
Higher susceptibility of somatostatin 4 receptor gene-deleted mice to chronic stress-induced behavioral and neuroendocrine alterations
The somatostatin 4 receptor (sst 4 ) is widely expressed in stress-related brain areas (eg
hippocampus, amygdala) and regulates the emotional behavior in acute situations. Since its …
hippocampus, amygdala) and regulates the emotional behavior in acute situations. Since its …
Reduced response to chronic mild stress in PACAP mutant mice is associated with blunted FosB expression in limbic forebrain and brainstem centers
Pituitary adenylate cyclase-activating polypeptide (PACAP) has been implicated in stress
adaptation with potential relevance in mood disorder management. PACAP deficient (KO) mice …
adaptation with potential relevance in mood disorder management. PACAP deficient (KO) mice …
Construct and face validity of a new model for the three-hit theory of depression using PACAP mutant mice on CD1 background
Major depression is a common cause of chronic disability. Despite decades of efforts, no
equivocally accepted animal model is available for studying depression. We tested the validity …
equivocally accepted animal model is available for studying depression. We tested the validity …
Peptidergic neurons of the Edinger–Westphal nucleus express TRPA1 ion channel that is downregulated both upon chronic variable mild stress in male mice and in …
…, A Kecskés, J Farkas, T Gaszner, V Csernus… - Journal of Psychiatry and …, 2022 - jpn.ca
Background: Transient receptor potential ankyrin 1 (TRPA1), a cation channel, is expressed
predominantly in primary sensory neurons, but its central distribution and role in mood …
predominantly in primary sensory neurons, but its central distribution and role in mood …