Dopamine and drug addiction: the nucleus accumbens shell connection

G Di Chiara, V Bassareo, S Fenu, MA De Luca… - …, 2004 - Elsevier
Microdialysis studies in animals have shown that addictive drugs preferentially increase
extracellular dopamine (DA) in the n. accumbens (NAc). Brain imaging studies, while extending …

Reward system and addiction: what dopamine does and doesn't do

G Di Chiara, V Bassareo - Current opinion in pharmacology, 2007 - Elsevier
Addictive drugs share with palatable food the property of increasing extracellular dopamine (DA),
preferentially in the nucleus accumbens shell rather than in the core. However, by …

Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments

V Bassareo, G Di Chiara - Neuroscience, 1999 - Elsevier
The nucleus accumbens septi is the major target of mesolimbic dopamine neurons originating
in the ventral tegmental area of the mesencephalon.[3]Studies involving experimental …

Differential influence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli …

V Bassareo, G Di Chiara - Journal of Neuroscience, 1997 - Soc Neuroscience
Feeding a novel food (Fonzies) to rats fed ad libitum with standard food increased
extracellular dopamine (DA) in the medial prefrontal cortex (PFCX) and in the medial nucleus …

Differential expression of motivational stimulus properties by dopamine in nucleus accumbens shell versus core and prefrontal cortex

V Bassareo, MA De Luca, G Di Chiara - Journal of neuroscience, 2002 - Soc Neuroscience
The response of extracellular dopamine (DA) and its relationship to motivational valence (positive
or negative) and novelty of motivational stimuli was investigated by brain microdialysis …

Modulation of feeding‐induced activation of mesolimbic dopamine transmission by appetitive stimuli and its relation to motivational state

V Bassareo, G Di Chiara - European Journal of Neuroscience, 1999 - Wiley Online Library
We have previously shown in non‐deprived rats that feeding of an unfamiliar palatable food
(Fonzies ® ) phasically stimulates in vivo dopamine (DA) transmission in the medial nucleus …

Drug addiction as a disorder of associative learning: role of nucleus accumbens shell/extended amygdala dopamine

G DI CHIARA, G Tanda, V BASSAREO… - Annals of the New …, 1999 - Wiley Online Library
Conventional reinforcers phasically stimulate dopamine transmission in the nucleus accumbens
shell. This property undergoes one‐trial habituation consistent with a role of nucleus …

A role for dopamine D1 receptors of the nucleus accumbens shell in conditioned taste aversion learning

S Fenu, V Bassareo, G Di Chiara - Journal of Neuroscience, 2001 - Soc Neuroscience
The involvement of dopamine (DA) in conditioned taste aversion (CTA) learning was studied
with saccharin or sucrose as the conditioned stimulus (CS) and intraperitoneal lithium as …

Differential impact of pavlovian drug conditioned stimuli on in vivo dopamine transmission in the rat accumbens shell and core and in the prefrontal cortex

V Bassareo, MA De Luca, G Di Chiara - Psychopharmacology, 2007 - Springer
… by us to food conditioning (Bassareo and Di Chiara 1997, 1999b… the present ones (Bassareo
and Di Chiara, in preparation). … test this possibility (Bassareo and Di Chiara, in preparation). …

Mianserin markedly and selectively increases extracellular dopamine in the prefrontal cortex as compared to the nucleus accumbens of the rat

G Tanda, V Bassareo, D Chiara - Psychopharmacology, 1996 - Springer
The atypical antidepressant mianserin, administered at doses of 1, 5 and 10 mg/kg SC, dose-dependently
increased up to about 6 times extracellular dopamine in the medial prefrontal …