Placebo may yield beneficial effects that are indistinguishable from those of active medication,
but the factors underlying proneness to respond to placebo are widely unknown. Here, we …

Converging lines of evidence suggest that the pathophysiology of pain is mediated to a
substantial degree via allostatic neuroadaptations in reward- and stress-related brain circuits. …

This study investigated the effects of anxiety on nonverbal aspects of speech using data
collected in the framework of a large study of social phobia treatment. The speech of social …

Importance Serotonin is involved in negative affect, but whether anxiety syndromes, such as
social anxiety disorder (SAD), are characterized by an overactive or underactive serotonin …

Social anxiety disorder (SAD) can come in different forms, presenting problems for diagnostic
classification. Here, we examined personality traits in a large sample of patients (N = 265) …

The amygdala is a key structure in the pathophysiology of anxiety disorders, and a putative
target for anxiolytic treatments. Selective serotonin reuptake inhibitors (SSRIs) and placebo …

It has been extensively debated whether selective serotonin reuptake inhibitors (SSRIs) are
more efficacious than placebo in affective disorders, and it is not fully understood how SSRIs …

Background Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for
depression and anxiety, but their efficacy relative to placebo has been questioned. We aimed …

The prevalence of migraine has an exponential trajectory that is most obvious in young females
between puberty and early adulthood. Adult females are affected twice as much as males…

“The cure for the headache was a kind of a leaf, which required to be accompanied by a charm,
and if a person would repeat the charm at the same time that he used the cure, he would …