The science of large-scale brain networks offers a powerful paradigm for investigating
cognitive and affective dysfunction in psychiatric and neurological disorders. This review …

The insula is a brain structure implicated in disparate cognitive, affective, and regulatory
functions, including interoceptive awareness, emotional responses, and empathic processes. …

Functional imaging studies have shown that certain brain regions, including posterior
cingulate cortex (PCC) and ventral anterior cingulate cortex (vACC), consistently show greater …

Recent functional imaging studies have revealed coactivation in a distributed network of
cortical regions that characterizes the resting state, or default mode, of the human brain. Among …

An understanding of how the human brain produces cognition ultimately depends on
knowledge of large-scale brain organization. Although it has long been assumed that cognitive …

Math anxiety is a negative emotional reaction to situations involving mathematical problem
solving. Math anxiety has a detrimental impact on an individual’s long-term professional …

Autism spectrum disorders (ASDs) represent a formidable challenge for psychiatry and
neuroscience because of their high prevalence, lifelong nature, complexity and substantial …

Objective Clinical data suggest that abnormalities in the regulation of emotional processing
contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities …

Variations in neural circuitry, inherited or acquired, may underlie important individual differences
in thought, feeling, and action patterns. Here, we used task-free connectivity analyses to …

Cognitively demanding tasks that evoke activation in the brain's central-executive network (CEN)
have been consistently shown to evoke decreased activation (deactivation) in the …